نتایج جستجو برای: bistable system
تعداد نتایج: 2233849 فیلتر نتایج به سال:
Stochastic resonance is studied in a one-dimensional array of overdamped bistable oscillators in the presence of a local subthreshold periodic perturbation. The system can be treated as an ensemble of pseudospins tending to align parallel which are driven dynamically by an external periodic magnetic field. The oscillators are subjected to a dynamic white noise as well as to a static topological...
Sonic hedgehog (Shh) controls critical cellular decisions between distinct fates in many systems, particularly in stem cells. The Shh network functions as a genetic switch, and we have theoretically and computationally analyzed how its structure can endow it with the ability to switch fate choices at a threshold Shh concentration. The network is composed of a positive transcriptional feedback l...
Dienstag, 14. Juli 2015 17.15 Uhr Stuttgarter Physikalisches Kolloquium Max-Planck-Institut für Festkörperforschung Max-Planck-Institut für Intelligente Systeme Fachbereich Physik, Universität Stuttgart
Transitions between steady states of a multi-stable stochastic system in the perfectly mixed chemical reactor are possible only because of stochastic switching. In realistic cellular conditions, where diffusion is limited, transitions between steady states can also follow from the propagation of travelling waves. Here, we study the interplay between the two modes of transition for a prototype b...
The general failure of neuroprotectants in clinical trials of ischemic stroke points to the possibility of a fundamental blind spot in the current conception of ischemic brain injury, the "ischemic cascade". This is the fourth in a series of four papers whose purpose is to work towards a revision of the concept of brain ischemia by applying network concepts to develop a bistable model of brain ...
We study the effects of a high-frequency (HF) signal on the response of a noisy bistable system to a low-frequency subthreshold sinusoidal signal. We show that, by conveniently choosing the ratio of the amplitude of the HF signal to its frequency, stochastic resonance gains greater than unity can be measured at the low-frequency value. Thus, the addition of the HF signal can entail an improveme...
This article recounts the development of a stand-alone CAD platform, the IDIIOM. The IDIIOM was developed during the mid-1960s at Information Displays, Inc. (IDI), then in Mt. Vernon, N.Y. According to its creators, the IDIIOM was the first general-purpose design workstation, the first commercial CADD platform, and the first software drafting package to operate on its own computer without commu...
Dynamic interactions between RhoA and Rac1, members of the Rho small GTPase family, play a vital role in the control of cell migration. Using predictive mathematical modeling, mass spectrometry-based quantitation of network components, and experimental validation in MDA-MB-231 mesenchymal breast cancer cells, we show that a network containing Rac1, RhoA, and PAK family kinases can produce bista...
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