The ability of pathogens to evade host antimicrobial mechanisms is crucial to their virulence. The dimorphic fungal pathogen Blastomyces dermatitidis can infect immunocompetent patients, producing a primary pulmonary infection that can later disseminate to other organs. B. dermatitidis possesses a remarkable ability to resist killing by alveolar macrophages. To date, no mechanism to explain thi...

chemical constituents of the essential oil of flowers of lavandula officinalis chaix. growing in isfahan, iran, were studied by tlc and gas chromatography-mass specrtometery (gc-ms) methods. twelve components which constitute 94.8% of the examined oil were identified. the main constituents were linalool (34.1%), 1,8-cineole (18.5%), borneol (14.5%), camphor (10.2%), terpinen-4-ol (4.5%), linaly...

PURPOSE The study objective was to investigate the production of NO, cGMP and superoxide anion radical by neutrophils, and to examine alterations in serum or plasma total nitric oxide, MDA and cGMP levels in B-CLL patients. MATERIAL AND METHODS PMNs were isolated from 20 patients with B-CLL. Total nitrite was measured in cell supernatants and serum by Griess method. The generation of superoxi...

Two patients with asymptomatic vitamin B(12) deficiency developed a peripheral neuropathy 6-7 weeks after exposure to nitrous oxide during general anaesthesia, and 3 and 11 days after receiving cyclophosphamide. The serum B(12) concentration was less than 20 pmol/l and the symptoms resolved after B(12) replacement. We believe that the neurological symptoms were triggered by exposure to nitrous ...