Several cases are described in which the chelate effect contributes to binding and catalysis. In the first examples, dimers made up of linked cyclodextrins show very strong selective substrate binding, and with catalytic groups in the linkers they are effective catalysts of reactions of bound substrates. In later examples, chelate binding of transition states by a base and an acid produce effec...

Density functional theory (DFT) calculations are presented on biomimetic model complexes of cysteine dioxygenase and focus on the effect of axial and equatorial ligand placement. Recent studies by one of us [Y. M. Badiei, M. A. Siegler and D. P. Goldberg, J. Am. Chem. Soc. 2011, 133, 1274] gave evidence of a nonheme iron biomimetic model of cysteine dioxygenase using an i-propyl-bis(imino)pyrid...

A universal label-free detection of bioanalytes can be performed with biomimetic quartz crystal microbalance (QCM) coatings prepared by imprinting strategies. Bulk imprinting was used to detect the endocrine disrupting chemicals (EDCs) known as estradiols. The estrogen 17β-estradiol is one of the most potent EDCs, even at very low concentrations. A highly sensitive, selective and robust QCM sen...

In recent years, the use of biomimetic membranes that incorporate membrane proteins, i.e., biomimetic-hybrid membranes, has increased almost exponentially. Key membrane proteins in these systems have been aquaporins, which selectively permeabilize cellular membranes to water. Aquaporins may be incorporated into synthetic lipid bilayers or to more stable structures made of block copolymers or so...

We present the rapid-prototyping of type I collagen micropatterns on poly-dimethylsiloxane substrates for the biomimetic confinement of cells using the combination of a surface oxidation treatment and 3-aminopropyl triethoxysilane silanisation followed by glutaraldehyde crosslinking. The aim of surface treatment is to stabilise microcontact printing transfer of this natural extracellular matrix...

The integration of biomimetic robots in a fish school may enable a better understanding of collective behaviour, offering a new experimental method to test group feedback in response to behavioural modulations of its 'engineered' member. Here, we analyse a robotic fish and individual golden shiners (Notemigonus crysoleucas) swimming together in a water tunnel at different flow velocities. We de...

Mimicry in the field of science involves reproducing or copying a model, a reference. If we as dentists want to replace what has been lost, we need to agree on what is the correct reference. The accepted frame of reference must be the same for the entire profession, and it should be timeless and unchanging success. Age, disease and traditional restorations can cause further problems to the exis...

The next great wave of innovation and development for implantable medical devices focuses on surface engineering. This would enhance their performance, restore lost functions and ultimately reduce pain. Biomimetic coating is a promising approach, used in that concern. In the present work, an attempt was made to develop the function of the biomimetic coating rather than the classical biocompatib...