In this study, nineteen different Streptomyces strains were isolated from oil-contaminated surface soil at Ataş Oil Terminal in Turkey. Biodegradation and Restriction Fragment Length Polymorphism tests (RFLP) used for selecting isolates. The isolates belonging to the genus confirmed by 16S rDNA analysis. 1592r, 1492r, 800r, 518f, 27f primers chosen gene amplifying sequencing. Then 93-unit chara...

Type 2 diabetes mellitus (T2DM) became the most prevalent health problem. Almost half of world's people are ignorant that have diabetes. Menopause occurs as an important alteration in women through which take place change sex hormones, distribution fat،s body, and metabolism, altogether participate metabolism disease such type mellitus. Several studies appeared association between TCF7L2 gene d...

Obesity is a multifactorial disease whose onset and development are shaped by the individual genetic background. The melanocortin 4 receptor gene (MC4R) involved in regulation of food intake energy expenditure. Some single nucleotide polymorphisms (SNPs) this related to obesity metabolic risk factors. present study was undertaken assess relationship between three polymorphism SNPs, namely, rs17...

AIM To investigate the association of peroxisome proliferator-activated receptor gamma (PPARG) Pro12Ala polymorphism with polycystic ovary syndrome (PCOS) and its effect on the metabolic parameters in PCOS women. METHODS The study used PCR to identify the presence of the PPARG Pro12Ala polymorphism in 100 PCOS women and 120 age-matched healthy women. All participants were subjected to anthrop...

We have examined the genetic polymorphism previously reported to be associated with the sickle-cell (beta s) gene. The polymorphism involves an alteration of the DNA sequence 3' to the beta-globin gene as detected with the restriction endonuclease, Hpa I. In normal individuals, the beta-globin gene is contained within a DNA fragment of 7.6 kilobases (kb), whereas 87% of individuals with sickle-...

I show that detectable polymorphism of host resistance and parasite host-range is a poor guide to the specificity of a host-parasite interaction. I analyze a simple haploid model to support this claim. The model assumes that the true specificity is " matching-allele " in which each of n host alleles causes resistance to only one of n different parasite alleles. The detectable polymorphism in sa...

OBJECTIVE To investigate the associations between polymorphisms in the promoter of the tumour necrosis factor-alpha (TNF-alpha) gene and gout. METHODS The polymorphisms -308G/A and -863C/A in the TNF-alpha gene were determined in 106 gout patients and 159 healthy controls among male Taiwanese using the Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP) method. The b...

BACKGROUND Polycystic ovarian syndrome (PCOS) is a complex, heterogeneous disorder of uncertain etiology with strong genetic background. Insulin resistance is present in the majority of PCOS cases with linkage and association between single nucleotide polymorphisms of insulin receptor (INSR) gene and PCOS. OBJECTIVE To examine whether the exon 17 of INSR gene contributes to genetic susceptibi...

It is well known that serum paraoxonase (PON1) plays an important role in the protection of LDL from oxidation. PON1 55 polymorphism is currently investigated for its possible involvement in cardiovascular diseases. The objective of our study is to verify if PON1 55 polymorphism is associated with risk of acute coronary syndrome (ACS) and with biochemical myocardial ischemia markers, such as tr...