Work on radioautographic localization of RNA synthesis has been reviewed by Prescott (1). The findings with this method show good correspondence with biochemical evidence by indicating the nucleus as the presumptive site of RNA synthesis, and the probability of transport of RNA from the nucleus to the cytoplasm has been established. The method has been applied by Nossal et al. (2) in semiquanti...

In this study we evaluated biochemical blood serum parameters and the association of Cyclin-dependent kinase 5 (CDK5) gene polymorphisms with the risk of Alzheimer's disease (AD) in the Polish population. We observed an elevated total cholesterol, low-density lipoproteins (LDL) and homocysteine levels and lower concentrations of high-density lipoproteins (HDL) and vitamin B12 in AD patients. Ho...

The objective of the study was to evaluate the cardioprotective activity of flax lignan concentrate (FLC) in isoprenalin (ISO) induced cardiotoxicity in rats. Male Wistar rats (200-230 g) were divided into three groups. Group I: control, Group II: isoprenalin, Group III: FLC (500 mg/kg, p.o.) orally for 8 days and in group II and III isoprenalin 5.25 mg/kg, s.c. on day 9 and 8.5 mg/kg on day 10...

Ecological adaptations to seasonal changes are often observed in the phenotypic traits of plants and animals, and these adaptations are usually expressed through the production of different biochemical end products. In this study, ecological adaptations are observed in a biochemical pathway without alteration of the end products. We present an alternative principal pathway to the characteristic...

Cisplatin is a common chemotherapeutic agent that used for treatment of many solid cancers. Rapid identification of chemotherapy resistance is very important and may lead to effective treatment plan. Spectroscopy techniques, such as infrared spectroscopy, which are sensitive to biochemical composition of samples, have shown potentials to discriminate tissues. Developing in Fourier transform inf...

BACKGROUND Thermal injury is associated with several biochemical and histopathological alteration in tissue. Analysis of these objective parameters in research and clinical field are common to determine healing rate of burn wound. Negative pressure wound therapy has been achieved wide success in treating chronic wounds. This study determines superficial burn wound healing with intermittent n...

This study was designed to investigate the clinico-haemato-biochemical, rumen fl uid and peritoneal fl uid alteration in buffaloes with peritonitis. Buffaloes with peritonitis had anorexia, dehydration, abdominal distension, ruminal atony, pain, fever, reduced milk yield and loss of defecation. Pungent smelling peritoneal fl uid was yielded on abdominocentesis. Hemato-biochemical alterations re...

Effect of pH on Metabolism and Ultrastructure of Guinea Pig Cerebral Cortex Slices • Lactic acidosis is a prominent biochemical alteration which follows cerebral ischemia and is of sufficient degree to result in pH decrease in involved and adjacent tissue. Because of the significance of acidosis in the cerebral ischemic process, we have investigated ultrastruclural changes and some biochemical ...

Extract of Methanol:ethanol (70:30) of Prunus domestica was prepared and tested for its hepatoprotective effect against Paracetamol and CCl4 induced hepatitis in rats . Alteration in the levels of biochemical markers of hepatic damage like SGPT, SGOT, ALP,Total bilirubin, direct bilirubin and tissue LPO, GSH, catalase and SOD were tested in both treated and untreated groups. Paracetamol (2 g/kg...