The interleukin-6 (IL-6) signal is transduced through membrane-anchored gp130, which is associated with IL-6 receptor (IL-6R) in the presence of IL-6. Soluble forms of gp130 (sgp130) with molecular weights of 90 and 110 Kd were found in human serum. In the presence of recombinant IL-6 (rIL-6), serum sgp130 were capable of associating with serum sIL-6R. By the sandwich enzyme-linked immunosorben...

Transcription from the mouse mammary tumor virus (MMTV) promoter can be induced by progestins. The progesterone receptor (PR) binds to a cluster of five hormone responsive elements (HREs) and activates the promoter by synergistic interactions with the ubiquitous transcription factor, nuclear factor 1 (NF1). Progesterone treatment of cells in culture leads to activation of the Src/Ras/Erk/Msk1 c...

The design criteria of biological aerated filter (BAF) were reviewed in order to design an effective process for organic and inorganic contaminants removal in drinking water, particularly, COD and ammonia removal. The review was mainly focused on the height and diameter dimensions for the BAF process system as well as the removal efficiency and the type of media used. In addition, the review al...

In this study, the potential use of sewage sludge (SS) as a fertilizer source for cultivated Dhaincha (Sesbania bispinosa (Jacq.) W.Wight) crops was investigated. Field experiments were conducted using different doses SS such 0% (T0), 5% (T1), 10% (T2), and 15% (T3) to amend soil (w/w). The findings showed that amended with significantly (p < 0.05) improved response parameters S. an increase...

Subcellular trafficking within host cells plays a critical role in viral life cycles, including influenza A virus (IAV). Thus targeting relevant subcellular compartments holds promise for effective intervention to control the impact of influenza infection. Bafilomycin A1 (Baf-A1), when used at relative high concentrations (≥10 nM), inhibits vacuolar ATPase (V-ATPase) and reduces endosome acidif...

We report on a study of the light yield and surface treatment of barium fluoride (BaF2) scintillation crystals. Using a bialkali photocathode the photoelectron (p.e.) yield of BaF, crystals was measured to be 130 p.e./MeV for the fast components and 700 p.e./MeV for the slow component. A somewhat hygroscopic nature for the BaF, is found. Teflon film was found to be the best wrapping material fo...

BaF, scintillator detectors are now in common use for the measurement of y-rays over a wide energy range because of the relatively high detection efficiency and the fast response which allows subnanosecond timing [1,2]. The BaF, scintillation light consists primarily of two components with decay times of or = 600 ps and TV = 620 ns [2], and the ratio of the intensities associated with each of t...

Powerful branch predictors along with a large branch target buffer (BTB) are employed in superscalar and simultaneous multi-threading (SMT) processors for instruction-level parallelism and thread-level parallelism exploitation. However, the large BTB not only dominates the predictor energy consumption, but also becomes a major roadblock in achieving faster clock frequencies at deep sub-micron t...

Predicting the bioavailability and effects of metals in sediments is of major concern in context with sediment risk assessment. This study aimed to investigate the bioavailability and molecular effects of metals spiked into riverine sediments to zebrafish (Danio rerio) embryos. Embryos were exposed to a natural and an artificial sediment spiked with cadmium (Cd), copper (Cu), nickel (Ni) and zi...

Dynamic control of gene expression is essential for the development of a totipotent zygote into an embryo with defined cell lineages. The accessibility of genes responsible for cell specification to transcriptional machinery is dependent on chromatin remodelling complexes such as the SWI\SNF (BAF) complex. However, the role of the BAF complex in early mouse development has remained unclear. Her...