stem cells are naïve or master cells. this means they can transform into special 200 cell types as needed by body, and each of these cells has just one function. stem cells are found in many parts of the human body, although some sources have richer concentrations than others. some excellent sources of stem cells, such as bone marrow, peripheral blood, cord blood, other tissue stem cells and hu...

recently, cell therapy has sparked a revolution in ischemic heart disease that will in the future help clinicians to cure patients. earlier investigations in animal models and clinical trials have suggested that positive paracrine effects such as neoangiogenesis and anti-apoptotic can improve myocardial function. in this regard the royan cell therapy center designed a few trials in collaboratio...

introduction:first, definition the stem cell refers to those cells that are still not clear and are not equipped for a particular task. these cells have proliferative properties and  ability to differentiate into other types of cells have become. this characteristic of stem cells to self-directed has absorbed professional opinion that extensive research is done in this regard. nowadays, stem ce...

liver failure, in an acute or chronic form, is a growing health problem ranking as one of the leading causes of death worldwide. inborn errors of metabolism characterized by defects in hepatic enzymes or other proteins with metabolic functions, such as receptors or transporters accompanied with environmental factors involve etiology and presentation of liver failure. currently, the only establi...

background currently, clinical endodontics includes procedures that are based on the ability of stem cells to accomplish repair (eg, direct pulp capping, apexogenesis, apexification, and even pulpal regeneration). an attempt is made to critically assess the current status in pulp regeneration therapy. methods: systematically, 2 distinctly different strategies exist involving stem cells for the ...

tissue-engineered biomaterials have existed approximately 40 years as simple biomimetic structures. replacement of human tissue with new tissue can be accomplished by generating replacements outside of the body or in situ in the body. in each case, the key elements are described as the tissue engineering triad of scaffolds, cells, and signals. scaffolds can be produced synthetically or derived ...

introduction: adult stem cells are the group of cells which conserve their nature in tissues and organs among other cells. in recent years, the researchers reported the existence of stem cells on the bulge of hair follicles near to the smooth muscle. it is possible to differentiate these stem cells to neural cells by induction of shh, fgf, and ra factors. because of existence of these factors i...

introduction: mechanical stimulation of human mesenchymal stem cells has demonstrated changes in many cell behaviours such as adhesion, migration, growth and differentiation through mechanotransductive pathways. these include experiments on effect of nanotopography 1, shear stress, stiffness of extracellular matrix 2, strain, stress and acoustic wave energy 3 on cells. in this research we were ...

cancer stem cells (cscs) have been identified as rare cellular populations in many cancers, including leukemia and solid tumors. this minor subpopulation of cancerous cells is immortal tumor-initiating cells which thought to be responsible for cancer initiation, progression, metastasis, recurrence and drug/radiation resistance. low proliferative rate, high self-renewing capacity, differentiatio...

introduction: the use of cord stem cells, as a cell source for bone marrow reconstruction in patient under hematopoietic stem cell transplantation is enhancing. the amount of cd34+cells collected from cord blood compared to peripheral blood and bone marrow are less, but their collectionprocesure is easier. delay in freezing has negative effect on cells surveillance and reduce their ability in t...