BACKGROUND Specificity of canine pancreatic lipase immunoreactivity (cPLI) assays in dogs with hyperadrenocorticism (HAC) is unknown. HYPOTHESIS Results of cPLI assays differ for clinically healthy dogs and dogs with HAC. ANIMALS Seventeen healthy dogs and 20 dogs with HAC diagnosed by ACTH stimulation test results without evidence of clinical pancreatitis. METHODS Dogs were enrolled betw...

The fluorescein dilaurate test, a non-invasive test of exocrine pancreatic function, was carried out on 21 children with cystic fibrosis and pancreatic exocrine insufficiency, and 12 healthy siblings. The test clearly discriminated between the patients with cystic fibrosis and severe exocrine pancreatic insufficiency and the normal control subjects.

The anti-inflammatory drug flurbiprofen speeds the repair of cigarette smoke-induced bronchial secretory cell metaplasia (SCM) in rats. We tested whether flurbiprofen would prevent or mitigate the development of elastase-induced bronchial SCM in hamsters. Twice daily injections of flurbiprofen (4 or 6 mg.kg-1.day-1) were begun immediately after intertracheal instillation of porcine pancreatic e...

The current case report presents a rare complication of a significant pancreatic tail necrosis following proximal splenic artery embolization in a 32-year-old male patient involved in a motorcycle accident. Proximal angiographic embolization of the splenic injury after trauma is a widely accepted method with excellent success rate; however, possible complications may occur and has been describe...

We present a 16-year-old boy with complete major pancreatic duct disruption in pancreatic neck. According to the American Association of Surgical Trauma Classification, the patient was diagnosed with pancreatic injuries grade IV and pseudocyst which was managed successfully by way of Ultrasound-guided percutaneous catheter drainage.

Autoimmune pancreatitis (AIP) is treatable with steroids, but relapse is frequent. The efficacy of steroid pulse therapy has been shown for various autoimmune diseases, but has not become established therapy. In this study, we reviewed the efficacy of steroid pulse therapy in 24 subjects who were diagnosed with AIP type 1 at our hospital. Patient characteristics, time-course of serum IgG4, and ...

EDITORIAL, COMMENT The study of malabsorption in Uganda, East Africa, has revealed that the majority of patients who have steatorrhoea suffer from exocrine pancreatic disorders. The differing incidence of malabsorption syndromes in a hospital community in Kampala, Uganda, has been compared with the incidence in both temperate and tropical climates and the clinical and laboratory features of thi...

Tuberculosis, in its extrapulmonary form, though emerging as a common clinical problem, rarely affects the pancreas. Its indolent course, vague symptomatology along with its non-specific laboratory and radiographic findings call for greater vigilance. We report a case of pancreatic tuberculosis, previously managed as recurrent alcohol related pancreatitis which showed symptomatic improvement fo...

In the last decade, an increased number of new cases of type 2 diabetes mellitus (T2DM) among patients who use statins have been reported. The aim of the present review is to compile the most relevant information about the risk of T2DM associated with the use and dose of different statins, especially based on meta-analysis considering different studies worldwide. To explain this relationship, s...

In the literature, CC presenting with PH has not been addressed adequately and there is a paucity of literature on CC complicated by PH. Gastrointestinal bleeding, splenomegaly or incidental discovery of esophageal varices led to the diagnosis of associated PH. Excision of CC and bilio-enteric bypass may not be feasible in those patients as there is a formation of massive collaterals in the reg...