BACKGROUND AND PURPOSE Vertebral artery origin stenosis prevalence. Most data on the prevalence of vertebral artery origin (VAo) disease is derived from hospital-based studies of patients with posterior circulation strokes and TIA. The prevalence of VAo disease in patients without posterior circulation symptoms or asymptomatic patients is poorly characterized. Our objective was to examine the p...

Middle cerebral artery occlusion (MCAO) by the intraluminal suture method is widely used to model ischemic stroke in rats. Current methods include transection or ligation of the external carotid or common carotid artery and thus result in partial restoration of perfusion after transient MCAO. Since incomplete reperfusion may influence recovery and thus confound studies of the impact of neuropro...

BACKGROUND We described a case of endoluminal stent placement for a cervical internal carotid artery stenosis in which access was obtained via the femoral bypass graft. CASE DESCRIPTION A 70-year-old man with known disease of the carotid, peripheral, and coronary arteries as well as congestive heart failure presented for endoluminal revascularization of a severe right internal carotid artery ...

Objective: The present study investigated the effects of a local Thai vegetable, Tiliacora triandra (Colebr.) Diels, also known as Yanang, against cerebral ischemia/reperfusion injury in mice. Materials and Methods: Thirty male ICR mice were divided into three experimental groups of BLCCAO + 10% Tween 80, BLCCAO + T. triandra 300 mg/kg, and BLCCAO + T. triandra 600 mg/kg. Cerebral ischemia/repe...

Complications of basilar skull fracture, such as carotid cavernous fistulae, meningitis, cerebrospinal fluid rhinorrhoea and otorrhoea, pneumatocele, and various cranial nerve disturbances, are well known (Gurdjian and Webster, 1958). In -addition, unilateral thrombosis of the internal carotid artery, both with and without basilar skull fracture, has frequently been reported after closed head a...

Background and Purpose: Ischemic episodes distal to an internal carotid artery occlusion are common. We undertook this study to look for evidence of transhemispheric passage of embolic material in this patient category as a mechanism for embolic events. Methods: Seven symptomatic patients with unilateral internal carotid artery occlusion and contralateral stenosis were examined by transcranial ...

In this study we determined mean-average wall shear stress values in the common carotid artery and assessed if there is a difference in mean-average WSS between: 1) patients with bilateral carotid bifurcation disease and 2) similar-aged volunteers with no evidence of disease. Sixteen patients with bilateral disease of the carotid bifurcation, and 8 volunteers were included in the study. Magneti...

Brain metabolites and arterial acid-base measurements were made one hr after bilateral carotid artery occlusion in 2 different models of hypertensive rats. Animals used included renovascular hypertensive rats (RHR) with an altered renin-angiotensin system and desoxycorticosterone hypertensive rats (DHR) with low plasma renin activity (PRA). The mean value for supratentorial lactate of 7.41 mM/k...

background: common carotid arterial stiffness can be assessed during carotid arterial ultrasonography, but its association with brachial stiffness, a well-defined cardiovascular risk factor, has not been clarified. the aim of this study was to examine the relationship between common carotid artery and brachial artery stiffness. methods: the static pressure-strain elastic modulus of the common c...

The cerebral ischemia in rats was induced by occluding bilateral common carotid arteries (BCCAO) for 30 min., followed by 45 min reperfusion. BCCAO caused significant depletion in superoxide dismutase, catalase, glutathione, glutathione peroxidase, glutathione-S-transferase, glutathione reductase and significant increase in lipid peroxidation along with severe neuronal damage in the brain. All ...