..................................................................................................................... 1 A. Two Digital Research Legs: Empirical Induction and Deductive Models ..... 2 B. Big Data for Development ........................................................................ 4 B1. CHARACTERISTICS OF BIG DATA...................................................................

We have previously shown endothelin (ET)-like immunoreactive staining in Weibel-Palade bodies, storage granules that are an integral component of the regulated secretory pathway in endothelial cells. These structures degranulate after chemical or mechanical stimuli that result in cytosolic calcium influx. We therefore investigated whether the regulated pathway might be an intracellular site inv...

This investigation explored the convergence between vocational interests as measured by the Strong Interest Inventory (Hansen & Campbell, 1985) and two competing personality models: the Big Five as measured by the NEO Personality Inventory–Revised (NEO-PI-R) (Costa & McCrae, 1992) and the Big Three as measured by the Multidimensional Personality Questionnaire (MPQ) (Tellegen, 1982; Tellegen & W...

The hallmark of classical Hodgkin lymphoma (cHL) is the presence of giant, mostly multinucleated Hodgkin-Reed-Sternberg (HRS) cells. Whereas it has recently been shown that giant HRS cells evolve from small Hodgkin cells by incomplete cytokinesis and re-fusion of tethered sister cells, it remains unsolved why this phenomenon particularly takes place in this lymphoma and what the differences bet...

Mesenchymal stem cells (MSCs) play a critical role in cartilage tissue engineering. However, MSCs-derived chondrocytes or cartilage tissues are not stable and easily lose the cellular and cartilage phenotype during long-term culture in vitro or implantation in vivo. As a result, chondrocytes phenotypic instability can contribute to accelerated ossification. Thus, it is a big challenge to mainta...

The use of the term 'big data' has grown substantially over the past several decades and is now widespread. In this review, I ask what makes data 'big' and what implications the size, density, or complexity of datasets have for the science of human development. A survey of existing datasets illustrates how existing large, complex, multilevel, and multimeasure data can reveal the complexities of...

Background: Table olives are nutritionally a complete food and considered as one of the oldest fermented products. This study aimed to evaluate the effect of Lactiplantibacillus plantarum 11 as a starter culture on the fermentation of table olives at two incubation temperatures 22 and 30 °C and different salt concentrations (0, 4, 8, and 12% m/v) of sodium chloride (NaCl). Methods: The ferment...

This study explored how personality and cultural variables influence subjective well-being (SWB) in two different U.S. ethnic groups: Asian Americans and European Americans. Structural equation modeling analyses supported a hypothesized culture→ personality model of SWB, in which the cultural syndromes of individualism and collectivism predict variations on personality dispositions (Big Five), ...