Abstract Background For radiopharmaceuticals, aseptic preparation in combination with filtration is the most commonly used sterilizing method. In general, production of radiopharmaceuticals needs to fulfil requirements good manufacturing practice. scope this work, we focused on positron emitter gallium-68 and therapeutically beta- gamma-emitter lutetium-177, as they are routinely for in-house s...

Fluorescent or metal halide lamps are widely used in therapeutic applications in dermatological diseases, with broadband or narrow band emission UVA/UVA1 (320-400 nm) obtained with suitable passive filters. Recently, it has been possible for us to use a new machine provided with solid state source emitting pulsed monochromatic UVA1 355 nm. In order to evaluate the effects of this emission on im...

A microwave-assisted extraction (MAE) procedure to isolate phenolic compounds from almond skin byproducts was optimized. A three-level, three-factor Box-Behnken design was used to evaluate the effect of almond skin weight, microwave power, and irradiation time on total phenolic content (TPC) and antioxidant activity (DPPH). Almond skin weight was the most important parameter in the studied resp...

To realize the potential of near-infrared (NIR) upconversion nanosensitizers for photodynamic therapy cancer, luminescence and energy transfer (ET) efficiency from emitter donors to photosensitizer acceptors need be improved. In current work, nanoparticles (UCNPs) with a core/emitter-active shell structure were constructed enhance not only emission but also ET surface-anchored photosensitizers....

BACKGROUND It is recognized that UV radiation produced apoptotic cells (sun burn cells) in the epidermis of mice. However, the relationship between apoptosis and cell proliferation after UV exposure in the skin of hairless mice are still unclear. OBJECTIVE To investigate the effects of ultraviolet (UV) radiation on molecular events associated with apoptosis and proliferation in SKH1-hr mouse ...

This study aims to develop a calibration system for radioactivity of beta sources using a calibration constant which derived from comparing measurement and simulation. It is hard to measure the activity of beta emitter isotope due to selfabsorption and scattering. So the activity involves high levels of uncertainty. The surface dose of Sr/Y-90 standard isotope was measured using extrapolation c...

Ultraviolet (UV) irradiation is a relevant environment factor to induce cellular senescence and photoaging. Both autophagy- and silent information regulator T1 (SIRT1)-dependent pathways are critical cellular processes of not only maintaining normal cellular functions, but also protecting cellular senescence in skin exposed to UV irradiation. In the present studies, we investigated whether modu...

Eosinophilic, polymorphic and pruritic eruption associated with radiotherapy (EPPER) can occur in cancer patients after irradiation. In this study, we characterized the clinical and histopathological features of pig skin that developed widespread polymorphic and pruritic skin lesions following localized 50 Gy gamma-irradiation. The pigs developed pruritus 5-7 weeks after irradiation, and infilt...

Data are presented demonstrating the differential radiosensitivity of the first and second-set responses of sublethally irradiated (670 rad) mice previously sensitized with allogeneic (H-2 difference), xenogeneic (rat) or both allogeneic and xenogeneic skin grafts: The secondset response is more radioresistant than is the first-set response; the second-set response to a xenogeneic graft remains...