peripheral blood t lymphocytes and their subsets were studied in 31 patients with beta thalassemia major (age 2-12years) and compared with 14 age-arid sex-matched healthy controls. three monoclonal antibodies (anti-cd3, anti cd-f, unti-cds) were simultaneously applied for detection of th (cd3-, cd4^), tsk (cd3+, cd8+) and th/ts ratio by flow-cytometry respectively. the results of this study sho...

background :highserum level of cancer antigen 15.3 (ca15.3) has been reported in some malignant and nonmalignant conditions including thalassemia major which could have been resulted from ineffective erythropoiesis. we aimed to evaluate the serum level of ca15.3 in carriers of beta-thalassemia by comparing them with cancer patients and healthy individuals.   methods : this cross-sectional study...

conclusions it can be concluded that the rsm is an effective method for the optimization of recombinant protein expression using synthetic genes in e. coli. results the proposed optimum fermentation condition consisted of 7.81 g l-1 glucose, od 600 nm prior induction 1.66 and induction temperature of 30.27°c. the model prediction of 0.267 g l-1 of rhifn-β and 0.961 g l-1 of acetate at the optim...

the undesirable effects and consequences of occupational fatal accidents have placed a great emphasis on applying preventive measures. this study was aimed to analyze and specify the latent causes of occupational fatal accidents in exir chemical plant, urmia - iran in 2008-2009. the analytical tripod-beta method was used. a geographic information system (gis) was then used to determine a list o...

conclusions in iran, hsct has been successfully adapted in routine clinical care. recently, new methods such as double cord blood and haploidentical transplantation have been used to treat many life-threatening diseases. results about 78.2% of the patients (2530 of 3237) remained alive between one to 211 months after stem cell transplantation. nearly, 21.8% (707) of our patients died after stem...

b ackground: in recent decades, extended spectrum beta-lactamase (esbl) producing bacteria have increased worldwide. the most important causative agents of nosocomial infections throughout the world, escherichia coli and klebsiella pneumoniae as main esbl-producing bacteria are so highly regarded. trends  in  the  treatment  of  infections  by such  bacteria  have  led  to  a  global concern. t...

background: patients with transfusional iron overload have depended on iron chelation therapy and improving chelation regimens have been of the highest priority. the aim of this study was to compare effect of combined versus monotherapy with deferoxamine (dfo) and deferiprone (dfp) in iron overloaded beta thalassemia (bt) major patients materials and methods we studied 36 bt major patients (mea...

background thalassemia is among the most common hematological diseases, but it has no definitive cure. the self-concept in adolescents with thalassemia major changes due to changes in their facial form. among the factors affecting the patient’s self-concept is social capital. objectives the study aims to examine the relationship between social capital and self-concept in adolescents with thalas...

post-harvest management of potatoes is a major challenge in iran. approximately 30% of the harvest is lostafter a few months of storage. the chemical methods for long term storage are not adequate to controldeterioration and also produce undesirable side effects. to address this issue, a study on radiationpreservation of potatoes was carried out. agria potato bulbs were irradiated using beta be...

conclusions our data showed that, the high prevalence of beta-lactamase genes among isolates, and it. our findings may provide useful insights in replace of the appropriate antibiotics and it may also prevents of esbls, mediated resistance problem. results from 145 strains of e. coli, 51(35.2%) and 61(42.1%) isolates were resistance to ceftazidime and cefotaxime, respectively. esbl production w...