Recognizing that a cure lies in timely detection, dermatologists strive to diagnose malignant melanoma (MM) at the earliest possible stage. The desire to achieve this goal without injudiciously and unnecessarily excising many benign lesions has led to numerous techniques that assist clinicians in differentiating nevi from MM, including clinical mnemonics and algorithms, optical imaging instrume...

Prostate gland is an unusual location for melanocytic lesions such as blue nevus. Typically, all three different types of melanchromatic lesions in the prostate, blue nevus, melanosis and malignant melanoma, are very rare and must be differentially diagnosed. These lesions are incidental findings in prostatic tissue biopsies and have a potential correlation with prostate adenocarcinoma. Blue ne...

Sir, We read with great interest the case report by Ahuja et al of a child, 6 weeks old, with multiple giant congenital melanocytic nevi and central nervous system melanosis. Neurocutaneous melanosis has been reported to manifest itself most commonly within the first two years of life and children with this entity have been born as still births or have been reported at as early as one month of ...

OBJECTIVES Melanocytic proliferations with Spitz differentiation present a difficult clinicopathologic dilemma, as their spectrum ranges from benign to malignant. Distinct entities include Spitz nevus, atypical Spitz nevus, and Spitzoid melanoma. Their histopathologic differentiation can be challenging, and cases of Spitzoid melanoma initially diagnosed as benign Spitz nevi are reported in the ...

Treatment of advanced melanoma with selective BRAF and MEK inhibitors is associated with a series of mucocutaneous side effects, among which morphological changes in preexisting nevi and the development of new melanocytic lesions, both benign and malignant. Objective was to describe the changes observed in melanocytic nevi under vemurafenib therapy, followed by combination therapy with dabrafen...

In this paper we propose a machine learning approach to classify melanocytic lesions as malignant or benign, using dermoscopic images. The lesion features used in the classification framework are inspired on border, texture, color and structures used in popular dermoscopy algorithms performed by clinicians by visual inspection. The main weakness of dermoscopy algorithms is the selection of a se...

INTRODUCTION The caruncle is a modified cutaneous tissue located at the inner canthus that contains hair follicles, accessory lacrimal glands, sweat glands and sebaceous glands. These different types of tissues can give rise to a wide variety of lesions that make the clinical diagnosis difficult. The aim of the study was to investigate the most common types of caruncle lesions and the clinical ...

BACKGROUND AND OBJECTIVE To examine the spectrum of eyelid neoplastic specimens obtained at the Beijing Tongren Eye Centre between 1997 and 2006. PATIENTS AND METHODS A total of 2,639 eyelid neoplasms were included in the study. RESULTS Of the 2,639 eyelid specimens, 2,276 (86.2%) were benign and 363 (13.8%) were malignant. The most common benign lesions were inflammatory lesions, melanocyt...

This paper presents a hierarchical classification system based on the kNearest Neighbors (kNN) classifier for classification of ten different classes of Malignant and Benign skin lesions from color image data. Our key contribution is to focus on the ten most common classes of skin lesions. There are five malignant: Actinic Keratosis (AK), Basal Cell Carcinoma (BCC), Squamous Cell Carcinoma (SCC...