introduction: myxofibrosarcoma was originally described as the myxoid variant of malignant fibrous histiocytoma (mfh), a high-grade and aggressive sarcoma, which is very uncommon in the head and neck region, with about 100 cases reported up to now. mfh occurring in the maxillary sinus is so rare that only 23 cases have been reported. we hereby report a case of myxofibrosarcoma in the maxillary ...

background & aim: malignant fibrous histiocytoma (mfh), is the most common soft tissue sarcoma in adults and is frequently seen is elderly. this lesion is so rare in bones and if seen, is common in long bones and the incidence of the lesion in maxillofacial bones is uncommon. in addition, maxilla is an unusual site for malignant fibrous histiocytoma (mfh). the aim of this article was to report ...

Two cases of malignant fibrous histiocytoma in which paraplegia was a major feature are presented. The histological features of the tumours are discussed with particular emphasis on the neural involvement. A brief review of the literature on the subject is included.

Primary intra-abdominal malignant mesenchymal tumours are very rare and there are not many cases of visceral malignant fibrous histiocytoma in the English literature. We report a new case of abdominal malignant fibrous histiocytoma presenting as abdominal pain and pyrexia of unknown origin in a 54 year old female followed by a brief review of literature. Presentation with pyrexia of unknown ori...

Retroperitoneal tumours are extremely rare neoplasms, most of them malignant. We described the case of a 48-year-old man with a large retroperitoneal mass detected during the study of a constitutional syndrome. The mass was treated surgerically and pathological diagnosis was malignant fibrous histiocytoma. Literature is reviewed and clinical features, histological findings, radiological techniq...

A rectus abdominis myocutaneous flap can provide a large amount of tissue for defect coverage. Rarely a flabby and redundant abdominal tissue was used as a huge extended flap. We report a case of recurrence malignant fibrous histiocytoma of the thigh which was radically resected. The resultant massive defect was success reconstructed with an extended pedicle inferiorly based rectus abdominis my...

Angiomatoid fibrous histiocytoma (AFH) is a rare disease that is often misdiagnosed initially. Patients can present with a clinical picture concerning for other diseases, and pathologic review is not always revealing. Molecular diagnostics are increasingly being utilized to detect gene fusions characteristic for AFH. Surgery remains the mainstay of management, and can effectively control local ...

Sepsis is a systemic inflammation caused by infection. The balance between M1-M2 macrophage polarization has an essential role in the pathogenesis of sepsis. However, the exact mechanism underlying macrophage polarization is unclear. We previously showed that levels of malignant fibrous histiocytoma amplified sequence 1 (MFHAS1) were significantly elevated in septic patients compared with those...

Comment. Although perineurial cell proliferation may be suspected histologically with routine hematoxylineosin staining, a definite identification needs the demonstration of perineurial cell features using immunohistochemical studies. The morphologic criteria include spindle cells with curved or wavy thin nuclei and thin, elongated cytoplasmic processes, arranged in lamellae, and a storiform gr...