Intestinal adenoma development in Apc(Min) mice is influenced by genetic background. We generated a congenic line between the CAST and B6 inbred strains to study the effects of a resistant CAST background in the absence of a major modifier locus, Modifier of Min 1 (Mom1(R)). Progeny from a CAST.B6 Mom1(R/S) x B6 Apc(Min/+) intercross were 110 or 200 days of age and screened for intestinal polyp...

Background. Although the size of colon polyps is an important risk factor for colorectal cancer, a standardized measurement technique has yet to be determined. In clinical practice, most endoscopists estimate polyp size by uncertain visual estimation; however, colonoscopic polypectomy is indicated for adenomatous polyps more than 5 mm in diameter. We have therefore developed a novel calibrated ...

Prospective investigation has been undertaken with the aim to study the frequency, location and age and sex distribution of various histological types of benign gastric epithelial polyps. Histological type--adenomatous, hyperplastic and fundic gland polyps--was diagnosed on the basis of at least three histological samples taken from the polyp. Biopsy samples were also taken from the antrum and ...

AIM Evaluation of the role of MLH-1 loss in serrated polyps of colon in a population of South of Iran. BACKGROUND There has been extensive change in classification and pathogenesis of serrated polyps of the colon during the last 10 years. The new classification is mostly based on the knowledge of the molecular pathogenesis and the rate of progression to colorectal cancer in these types of pol...

A colonoscopy survey of 620 patients with 1049 colon adenomas showed a predominantly left-sided distribution (77%). Of these lesions 97% were amenable to endoscopic removal or ablation. Sixty per cent of patients presented with rectal bleeding as their major symptom. There was agreement between radiology and colonoscopy in only 62% of patients, as many of the studies were single contrast barium...

An 84-year-old woman with advanced pharyngeal cancer underwent colonoscopy for intermittent rectal bleeding in October 2012. Colonoscopy disclosed two red sessile polyps in the rectum (Fig 1). The larger one was spherical with a smooth surface, measuring approximately 15 mm in diameter (Fig 2). Biopsy showed hyperplastic glands and marked proliferation of smooth muscle cells in the lamina propr...

PURPOSE This study aimed to evaluate the clinical features of juvenile polyp and the usefulness of polypectomy with entire colonoscopy in children. METHODS We retrospectively reviewed the medical records of 83 children who were diagnosed with having juvenile polyps. RESULTS The mean age of the patients was 6.5±3.7 (range 1.3-14.5 years) years. The male to female ratio was 2.1: 1. Eighty one...