In the obnoxious facility game, a location for an undesirable facility is to be determined based on the voting of selfish agents. Design of group strategy proof mechanisms has been extensively studied, but it is known that there is a gap between the social benefit (i.e., the sum of individual benefits) by a facility location determined by any group strategy proof mechanism and the maximum socia...

Medullary thyroid carcinoma (MTC) is a rare neuroendocrine tumor originating from parafollicular C cells of the thyroid and associated with mutations in the proto-oncogene REarranged during Transfection (RET). The prognosis of MTC depends on clinical stage, with a 95.6% 10-year survival rate among patients with localized disease and 40% among patients with advanced disease. Standard chemotherap...

Text pages 29 Tables 1 Figures 4 References 45 Word count: Abstract 190 Introduction 528

Regarding the costs related to the physicians writing ECG reports, the authors have informed that the cardiologists who analyze the ECGs take turns in shifts to cover the entire state of Minas Gerais. The cost of those professionals, however, has not been informed in the analyses performed in that article. Another important factor not specified in that article is whether all elective and emerge...

This paper addresses the question of optimal phenotypic plasticity as a response to environmental fluctuations while optimizing the cost/benefit ratio, where the cost is energetic expense of plasticity, and benefit is fitness. The dispersion matrix Σ of the genes’ response (H = ln|Σ|) is used: (i) in a numerical model as a metric of the phenotypic variance reduction in the course of fitness opt...

I njury is the most common cause of death in North Americans aged 1 to 45 and the most important cause of the loss of productive life for all Americans. Traumatic injury kills 93,000 people in the United States each year with about half dying before they reach the hospital. Profound neurologic injury is the most common cause of death in trauma centers and uncontrolled hemorrhage is the second, ...

The primary aim of breast cancer screening is to reduce breast cancer mortality, but screening also has negative side-effects as overdiagnosis. To evaluate a screening programme, both benefits and harms should be considered. Published estimates of the benefit-to-harm ratio, the number of breast cancer deaths prevented divided by the number of overdiagnosed breast cancer cases, varied considerab...

This study identifies and analyzes factors influencing canola plantation development in Tabriz and Marand Counties. The Censored Model was used to analyze cross-sectional data collected from 372 farmers using a questionnaire. Due to the weakness of the Tobit Model in separating factors affecting the adoption decision of farmers and factors affecting the rate of adoption, the Heckman Model was e...

The main concern of an olive grower is primarily to achieve more income and profits. A harvesting method having higher efficiency and better fruit and oil quality, but a higher operation cost leads to a lower benefit. A study was carried out to evaluate the techno-economic performances of Trunk Shaker (TS) and Mechanical Harvest Aid (MHA) shaker for harvesting the yellow and Manzanilla olive cu...