1Department of Cardiology, Beijing Daxing Hospital, Capital University of Medical Sciences, Beijing 102600, China 2Department of Cardiology, Beijing People’s Hospital, Beijing University, Beijing 100044, China 3Department of Cardiology, Beijing Tongren Hospital, Capital University of Medical Sciences, Beijing 107300, China 4Department of Cardiology, Datong Third Hospital, Datong Shanxi 037000, ...

To better understand the transmission and evolution of Mycobacterium tuberculosis (MTB) in Taiwan, six different MTB isolates (representatives of the Beijing ancient sublineage, Beijing modern sublineage, Haarlem, East-African Indian, T1, and Latin-American Mediterranean (LAM)) were characterized and their genomes were sequenced. Discriminating among large sequence polymorphisms (LSPs) that occ...

Tuberculosis is a serious public health concern especially in Africa and Asia. Studies describing strain diversity are lacking in the Free State region of South Africa. The aim of the study was to describe the diversity of Mycobacterium tuberculosis (M. tuberculosis) strain families in the Free State province of South Africa. A total of 86 M. tuberculosis isolates were genotyped using spoligoty...

BACKGROUND  The development of active tuberculosis disease has been shown to be multifactorial. Interactions between host and bacterial genotype may influence disease outcome, with some studies indicating the adaptation of M. tuberculosis strains to specific human populations. Here we investigate the role of the human leukocyte antigen (HLA) class I genes in this biological process. METHODS  ...

Accumulating evidence indicates that latency-associated Mycobacterium tuberculosis (Mtb)-specific antigens from the dormancy survival regulator regulon (DosR) may be promising novel vaccine target antigens for the development of an improved tuberculosis vaccine. After transcriptional profiling of DosR-related genes in the hyper-virulent Beijing Mtb strain K and the reference Mtb strain H37Rv, w...

An outbreak of multi-drug resistant (MDR) tuberculosis (TB) has been reported on Daru Island, Papua New Guinea. Mycobacterium tuberculosis strains driving this outbreak and the temporal accrual of drug resistance mutations have not been described. Whole genome sequencing of 100 of 165 clinical isolates referred from Daru General Hospital to the Supranational reference laboratory, Brisbane, duri...

In order to increase the luminosity of Beijing ElectronPositron Collider (BEPC), the single interaction point (SIP) schemes were adopted. Then the electron and positron beams were separated at the north IP and collided at the south IP. Some experiments were done during these years. The results are given in the paper.

Daily PM2.5 samples were collected at Shangdianzi (SDZ) regional site in Beijing-Tianjin-Hebei (BTH) region in 2015. Samples were subject to chemical analysis for organic carbon (OC), elemental carbon (EC), and major water-soluble inorganic ions. The annual average PM2.5 mass concentration was 53 ± 36 μg·m-3 with the highest seasonal average concentration in spring and the lowest in summer. Wat...

144 Metabolomics studies of chronic atrophic gastritis cold and heat syndrome M.L. Wang, C.L. Zheng, Y.W. Zhou, T.G. Liu, Y.B. Li, H. Xie, Y. Chang, W.C. Liu, G.G. Chen, X.L. Sun, Y.H. Zhao, Z.H. Li 1 Beijing Jiangong Hospital, Beijing 100054,China 2 Beijing Gulou Hospital of Traditional Chinese Medicine, Beijing 100009, China 3 Beijing University of Chinese Medicine, Beijing 100029,China 4 Bei...

Y. Hao, J. Liu, Y. Zhang, X. Wang, J. Zhang, and J. Fang Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, Beijing, China, People's Republic of, Dept. of Radiology, Peking University First Hospital, Beijing, Beijing, China, People's Republic of, College of Engineering, Peking University, Beijing, Beijing, China, People's Republic of, Dept. of Radiology, Peking Universi...