Triple-negative breast cancer (TNBC) studies have shown that neoadjuvant chemotherapy before surgery was effective in the minority of women, whereas the majority who had residual tumor had a relatively poor outcome. To identify the mechanism by which residual cancer cells survive chemotherapy, we initially conducted gene expression profiling using the CRL2335 TNBC cell line derived from a squam...

Every step we take in the digital world leaves behind a record of our behavior; footprint. Research has suggested that algorithms can translate these footprints into accurate estimates psychological characteristics, including personality traits, mental health or intelligence. The mechanisms by which AI generates insights, however, often remain opaque. In this paper, show how Explainable (XAI) h...

Introduction To investigate the mechanism underlying increased risk of subsequent neurodevelopmental disorders in children born to mothers with preeclampsia, we evaluated neurodevelopment offspring a preeclampsia rat model induced by administration N-nitro-L-arginine methyl ester (L-NAME) and identified unique protein signatures cerebrospinal fluid. Methods Pregnant rats received an intraperito...

This paper proposes the learning behavioral Petri nets (LBPN) to model learning behavior in web-based environments. Fully useful records of learning behaviors must contain their expended time and corresponding contents. Therefore, the LBPN extends the colored tokens of colored Petri nets to identify learners and learning contents, and raises the time variable to represent diverse learning times...

This article discusses the core curriculum for behavioral science, from the perspective of psychology, recommended by the Japanese Society of Behavioral Medicine and seeks to explain how the curriculum can be effectively implemented in medical and health-related departments. First, the content of the core curriculum is reviewed from the perspective of psychology. We show that the curriculum fea...

The consequence of treatment with antibiotics on the gut microbiota can be destructive. antibiotics, however, utilized to understand role host physiology. Earlier, we reported efficacy vancomycin in perturbation. We continued effect restoration kinetics perturbed immunity and behavior Th1 (C57BL/6)- Th2 (BALB/c)-biased mice. studied for two months following withdrawal both mice strains. analyze...

The role played by information and communication technologies in human life is growing the year. During current pandemic, systems have become an essential part of operations many industries around world. This has also brought a dynamic development solutions implemented Contact Center systems, which ensure quick contact with customers. paper presents how pace affects optimization selected Key Pe...