Joiner’s (2007) Interpersonal Theory of Suicide (IPTS) has shown promise in understanding the ongoing problem veteran suicide. Consistent with IPTS, it was hypothesized that perceived burdensomeness (PB) and thwarted belongingness (TB) would significantly predict suicidal ideation (SI), while acquired capability (AC) SI after controlling for effects PB TB on SI. It also Army veterans’ help-seek...

Treatment-emergent suicidal ideation and behavior are ongoing concerns with antidepressants. Vilazodone, currently approved for the treatment of major depressive disorder (MDD) in adults, has also been evaluated in generalized anxiety disorder (GAD). Post-hoc analyses of vilazodone trials were carried out to examine its effects on suicidal ideation and behavior in adults with MDD or GAD. Data w...

In this study, we examined whether the 5 Minnesota Multiphasic Personality Inventory-2-Restructured Form (MMPI-2-RF; Ben-Porath & Tellegen, 2008/2011) Suicidal/Death Ideation (SUI) items (93, 120, 164, 251, and 334) would provide incremental suicide-risk assessment information after accounting for information garnered from clinical interview questions. Among 229 forensic inpatients (146 men, 83...

The identification of genetic biomarkers facilitates the staging of brain disorders, their prognosis, choice of treatments and interventions, prediction of response, and prognosis of outcomes over a wide spectrum of symptoms associated with affective states, possibly optimizing clinical practice treatments and procedures. In this regard, epigenetic mechanisms mediate the effects of the environm...

BACKGROUND Previous studies indicate increased prevalences of suicidal ideation, suicide attempts, and completed suicide in Huntington's disease (HD) compared with the general population. This study investigates correlates and predictors of suicidal ideation in HD. METHODS The study cohort consisted of 2106 HD mutation carriers, all participating in the REGISTRY study of the European Huntingt...

Suicidal thinking is the basis for development of other forms and levels suicidal behaviour. According to available research, nature level ideation largely depend on situational factors. Changes limitations related COVID-19 pandemic can be viewed as a set factors that significantly contribute increased intensity behaviour in general particular. The study involved 87 students from Ukraine, Germa...

OBJECTIVE To survey the current approaches of clinical trial sponsors in prospective suicidal ideation and behavior assessments and challenges encountered. DESIGN An internet-based survey. SETTING Inclusion of prospective assessments of suicidal ideation and behavior in industry-sponsored clinical studies were required following the release of the September 2010 United States Federal Drug A...

BACKGROUND The importance of spirituality in coping with a terminal illness is becoming increasingly recognised. We aimed to assess the relation between spiritual well-being, depression, and end-of-life despair in terminally-ill cancer patients. METHODS 160 patients in a palliative care hospital with a life expectancy of less than 3 months were interviewed with a series of standardised instru...

This article describes the rationale, development, and validation of the Scale for Suicide Ideation (SSI), a 19-item clinical research instrument designed to quantify and assess suicidal intention. The scale was found to have high internal consistency and moderately high correlations with clinical ratings of suicidal risk and self-administered measures of self-harm. Furthermore, it was sensitiv...

The present study explored the relationship of scores on acculturative stress with those on depression and suicidal ideation among 26 male and 28 female Mexican-American students from a southern California high school. Subjects completed the SAFE acculturative stress scale, the Reynolds Adolescent Depression Scale, and the Suicidal Ideation Questionnaire-Junior. Analyses suggested that accultur...