In oral cancers, cytoplasmic BAG-1 overexpression is a marker of poor prognosis. BAG-1 regulates cellular growth, differentiation and survival through interactions with diverse proteins, including the vitamin D receptor (VDR), a key regulator of keratinocyte growth and differentiation. BAG-1 is expressed ubiquitously in human cells as three major isoforms of 50 kDa (BAG-1L), 46 kDa (BAG-1M) and...

Adaptive visualization can present user-adaptive information in such a way as to help users to analyze complicated information spaces easily and intuitively. We presented an approach called Adaptive VIBE, which extended the traditional reference point-based visualization algorithm, so that it could adaptively visualize documents of interest. The adaptive visualization was implemented by separat...

purpose the objectives of this study include: (1) determination of the attenuation of strike acceleration that tae kwon do sparring safety pads provide from kicks from olympic style tkd fighters, (2) the sex and weight differentiation in acceleration achieved within the thorax model with the roundhouse kicks. methods this prospective, observational study utilized 15 olympic style fighters from ...

SUMMARY New platelet storage systems, such as changes in the plastic of the storage bags, require validation. In this study, pooled buffy coat platelets stored in Fresenius/NPBI polyolefin bags were compared with those stored in Fresenius/NPBI butyryl-trihexyl citrate (BTHC) plasticized polyvinyl chloride (PVC). The CompoSelect thrombocyte polishing filter system (1000 mL polyolefin bag) and th...

Part of the cellular and physiological functions of BAG-1 (Bcl-2-associated athanogene 1) has been ascribed to the ability of this hsp70 (heat-shock protein 70) co-chaperone to regulate steroid receptor activity. BAG-1 has been reported to inhibit the GR (glucocorticoid receptor) and stimulate the androgen receptor, but to leave the activity of the MR (mineralocorticoid receptor) unchanged. Giv...

This paper describes the Barcelona Media Innovation Center participation in the 2nd International Competition on Plagiarism Detection. Particularly, our system focused on the external plagiarism detection task, which assumes the source documents are available. We present a two-step a approach. In the first step of our method, we build an information retrieval system based on Solr/Lucene, segmen...

purpose: to report a case of capsular bag distension syndrome (cbds) with solid material presenting eight years after cataract surgery. case report: a 58-years-old female who underwent an uneventful clear-cornea phacoemulsification with in-the-bag intraocular lens (iol) implantation in the right eye, presented with a chief complaint of blurred vision (va: 20/200) and cobweb like matter appearin...

BAG-1 is a multifunctional protein that blocks apoptosis and interacts with several types of proteins, including Bcl-2 family proteins, the kinase Raf-1, certain tyrosine kinase growth factor receptors, and steroid hor mone receptors, possibly by virtue of its ability to regulate the Hsp70/ Hsc70 family of molecular chaperones. Two major forms of the human and mouse BAG-1 proteins were detected...