نتایج جستجو برای: bacteriocidal effect

تعداد نتایج: 1641732  

پایان نامه :دانشگاه آزاد اسلامی - دانشگاه آزاد اسلامی واحد گرمسار - دانشکده علوم انسانی 1391

the present study was conducted to investigate the effect of implicit focus on form through input flooding and the effect of noticing, explicit focus on form on linguistic accuracy. to fulfill the purpose of the study, 86 iranian pre-intermediate efl learners of one of the language institutes were chosen by means of administering ket as the homogeneity test. these learners were pretested throug...

Journal: :Cancer research 2012
Shun X Ren Alfred S L Cheng Ka F To Joanna H M Tong May S Li Jing Shen Clover C M Wong Lin Zhang Ruby L Y Chan Xiao J Wang Simon S M Ng Lawrence C M Chiu Victor E Marquez Richard L Gallo Francis K L Chan Jun Yu Joseph J Y Sung William K K Wu Chi H Cho

Cathelicidins are a family of bacteriocidal polypeptides secreted by macrophages and polymorphonuclear leukocytes (PMN). LL-37, the only human cathelicidin, has been implicated in tumorigenesis, but there has been limited investigation of its expression and function in cancer. Here, we report that LL-37 activates a p53-mediated, caspase-independent apoptotic cascade that contributes to suppress...

2012
Hadas Hawlena Farrah Bashey Curtis M Lively

Bacteriocins are bacteriocidal toxins released by almost all bacteria. They are thought to have a narrow range of killing, but as bacteriocin-mediated interactions have been rarely studied at biologically relevant scales, whether this narrow range of action falls mostly within or mostly between coexisting species in natural communities is an open question with important ecological and evolution...

Journal: :Environmental Health Perspectives 1975
A F LeRoy

Platinum-metal oxidation catalysts are to be introduced in exhaust systems of many 1975 model-year automobiles in the U.S. to meet Clean Air Act standards. Small quantities of finely divided catalyst have been found issuing from prototype systems; platinum and palladium compounds may be found also. Although platinum exhibits a remarkable resistance to oxidation and chemical attack, it reacts ch...

2012
Shun X. Ren Alfred S.L. Cheng Ka F. To Joanna H.M. Tong May S. Li Jin Shen Clover C.M. Wong Lin Zhang Ruby L.Y. Chan Xiao J. Wang Simon S.M. Ng Lawrence C.M. Chiu Victor E. Marquez Richard L. Gallo Francis K.L. Chan Jun Yu Joseph J.Y. Sung William K.K. Wu Chi H. Cho

Cathelicidins are a family of bacteriocidal polypeptides secreted by macrophages and polymorphonuclear leukocytes (PMN). LL-37, the only human cathelicidin, has been implicated in tumorigenesis, but there has been limited investigation of its expression and function in cancer. Here, we report that LL-37 activates a p53-mediated, caspase-independent apoptotic cascade that contributes to suppress...

Journal: :The Journal of biological chemistry 1992
O P Kuipers H S Rollema W M Yap H J Boot R J Siezen W M de Vos

The small antimicrobial peptide nisin, produced by Lactococcus lactis, contains the uncommon amino acid residues dehydroalanine and dehydrobutyrine and five thio ether bridges. Since these structures are posttranslationally formed from Ser, Thr, and Cys residues, it is feasible to study their role in nisin function and biosynthesis by protein engineering. Here we report the development of an ex...

Journal: :The Journal of infectious diseases 2012
Dong Hyeok Kim Jeong Ju Lim Jin Ju Lee Dae Geun Kim Hu Jang Lee Wongi Min Kwang Dong Kim Hong Hee Chang Mehari Endale Man Hee Rhee Masahisa Watarai Suk Kim

BACKGROUND Brucella abortus can proliferate within professional and nonprofessional phagocytic host cells and thereby successfully bypass the bacteriocidal effects of phagocytes. However, the intracellular survival mechanism and factors of virulence are not fully understood. METHODS We have investigated the role of the regulator of G protein signaling 2 (RGS2), an intracellular calcium ([Ca(2...

2017
Daniel H. Haft Phillip G. Pierce Stephen J. Mayclin Amy Sullivan Anna S. Gardberg Jan Abendroth Darren W. Begley Isabelle Q. Phan Bart L. Staker Peter J. Myler Vasilios M. Marathias Donald D. Lorimer Thomas E. Edwards

During human infection, Mycobacterium tuberculosis (Mtb) survives the normally bacteriocidal phagosome of macrophages. Mtb and related species may be able to combat this harsh acidic environment which contains reactive oxygen species due to the mycobacterial genomes encoding a large number of dehydrogenases. Typically, dehydrogenase cofactor binding sites are open to solvent, which allows NAD/N...

2011
Seung-Hun Baek Alice H. Li Christopher M. Sassetti

Treatment of chronic bacterial infections, such as tuberculosis (TB), requires a remarkably long course of therapy, despite the availability of drugs that are rapidly bacteriocidal in vitro. This observation has long been attributed to the presence of bacterial populations in the host that are "drug-tolerant" because of their slow replication and low rate of metabolism. However, both the physio...

2005
YOSHITAKA SHINTO KEIRO ONO

Porous blocks of calcium hydroxyapatite ceramic were evaluated as delivery systems for the sustained release of antibiotics. We tested gentamicin sulphate, cefoperazone sodium, and fiomoxef sodium in powder form placed in a cylindrical cavity in calcium hydroxyapatite blocks, using in vitro studies of elution and in vivo studies in rats. Gentamicin sulphate gave a maximum concentration within t...

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