I review the development of the new set of MMPI-2 scales, the Restructured Clinical (RC) Scales (Tellegen et al., 2003). I identify several conceptual and methodological flaws in the construction of these scales, and I discuss the influence of a central shortcoming, the use of an atypical and depressively biased marker for unwanted ("first-factor") variance and its consequences for the RC Scale...

Tumor necrosis factor (TNF)-α, a pleiotropic cytokine that exerts a variety of effects, such as growth promotion, growth inhibition, angiogenesis, cytotoxicity, inflammation, and immunomodulation, has been implicated in several inflammatory conditions. It plays a significant role in many inflammatory diseases of lung. Given that there is significant literature supporting the pathobiologic role ...

Senior Associate in Anesthesia Children's Hospital Recently, Jevtovic-Todorovic and colleagues reported that the rat pups exposed to combination of isoflurane, midazolam and nitrous oxide developed significant neurodegeneration and delayed deficits in learning and memory testing 1. Previous investigations from the same group reported similar patterns of accelerated neurodegeneration in rat pups...

The assessment of the potential for sexual violence is one of three prongs that must be met to satisfy the requirements for civil confinement of dangerous sex offenders in the 21 U.S. jurisdictions that have these laws. In a recent issue of The Journal, Sreenivasan et al. argued that, because of a host of methodological problems, actuarial risk assessment methods in general and the Static-99 an...

apart from the breast milk, infant formula and baby weaning food have a special role in infant diet. infants and young children are very susceptible to amount of trace elements. copper and zinc are two elements that add in infant food. lead and cadmium are heavy metals that enter to food chain unavoidably. dpasv is a benefit and applicable method for measurement of trace elements in food produc...