OBJECTIVE Diagnosis of axillary nodal involvement is significant in the management of breast cancer as well as in predicting prognosis. In this prospective study, we evaluated the efficiency of US-guided fine needle aspiration biopsy (FNAB) in preoperative axillary staging of early breast cancer. MATERIAL AND METHODS Between January 2011 and July 2013, 46 women were prospectively enrolled in ...

Purpose: Our aim is to define the sonographic criteria for assessing involved axillary nodes and to evaluate the accuracy of axillary ultrasound in the staging workup of individuals with breast cancer. Materials and Methods: 35 patients with breast cancer were prospectively evaluated with preoperative ultrasonography (US) to determine the presence of axillary lymph node metastasis. We determine...

Background: The axillary and supraclavicular nodal volume treatment results in improvement of local control and survival after breast conserving surgery (BCS) or modified radical mastectomy (MRM). Studies on the depth of these nodes have questioned the consistent use of standard fields for all patients. This study was done to assess the dose delivery to these lymph nodes with conventional treat...

Management of the axilla is controversial. There has never been a widely agreed means of balancing an understanding of nodal status as prognostic information, the need to prevent axillary recurrence and the wish to avoid treatment-related morbidity, particularly arm lymphoedema. Balancing these conflicting requirements is difficult, particularly as the results of previous trials of locoregional...

Background. Sentinel node biopsy (SNB) represents the standard of care in breast cancer axillary evaluation. Our study aims to characterize the patterns of malignant cell distribution within the sentinel nodes (SN). Methods. In a retrospective IRB-approved study, we examined the anatomic location of the nodal area with the highest radioactive signal or most intense blue staining (hot spot) and ...

Correspondence to: Charalampos Seretis, MBBS, MSc. Russells Hall Hospital, Dudley Group of Hospitals NHS Foundation Trust, Pensnett Road, DY1 2HQ, Dudley, West Midlands, United Kingdom. Tel: +44 1384 456111, Fax: +44 1384244051, E-mail: [email protected]. Received : 26/06/2016; Accepted : 04/07/2016 The advent of sentinel lymph node biopsy (SLNB), in conjunction with tissue-sparing surgery and...

In this study, we evaluated the accuracy of a neural network in predicting 5-, 10- and 15-year breast-cancer-specific survival. A series of 951 breast cancer patients was divided into a training set of 651 and a validation set of 300 patients. Eight variables were entered as input to the network: tumor size, axillary nodal status, histological type, mitotic count, nuclear pleomorphism, tubule f...

Purpose. The value of nodal ratios (NRs) as a prognostic variable in breast cancer is continually being demonstrated. The purpose of this study was to use NR in patients with ≥4+ nodes to assess a correlation of NR with regional (lymph node) recurrence. Methods. Inclusion criteria was ≥8 nodes dissected with ≥4+ nodes after breast conservation therapy. Of 1060 patients treated from 1975 to 2003...