PURPOSE The most important prognostic variable for early stage breast cancer is the status of axillary lymph nodes. The aim of this study was to evaluate the diagnostic accuracy of preoperative magnetic resonance imaging (MRI) for metastatic axillary lymph node in breast cancer cases with post-operative sentinel lymph node biopsy (SLNB) results. MATERIALS AND METHODS Women aged between 21 and...

background: breast conservation therapy (bct) is the standard of care for early stage breast cancer. the procedure can be a challenge for the surgeon if the lesion is non-palpable. for excision of non-palpable breast lesions, they should be localized precisely before surgery. there are different techniques such as the wgl (wire guided localization), roll (radio-guided occult lesion localization...

Metastasis is a multistep process that is not well understood. Colonization of a secondary organ requires specific molecular alterations of the host microenvironment. To determine the temporal and spatial changes associated with metastatic dissemination to the axillary lymph nodes, gene expression profiles were compared between histologically normal lymph nodes from node-positive patients and t...

This study documents our initial experience for visualisation of sentinel lymph nodes (SLNs) with lymphoscintigraphy and intraoperative detection of SLN with the handheld gamma probe in patients with primary breast cancer. Fourteen women with palpable breast cancer had peritumoral injection of Tc labeled nanocolloid in four different regions. 1mCi of Tc labeled nanocolloid in 0.8 ml saline were...

AIM The aim of this study was to determine factors that predict non-sentinel axillary lymph nodes (NSLNs) metastases in breast cancer patients with positive sentinel node biopsy (SLNB). MATERIAL OF STUDY We reviewed the records of a consecutive series of 176 breast cancer patients who underwent SLNB at our institution. From the database we analysed those cases with one or more positive sentin...

In individuals with mammary carcinoma, the most relevant prognostic predictor of distant organ metastasis and clinical outcome is the status of axillary lymph node metastasis. Metastases form initially in axillary sentinel lymph nodes and progress via connecting lymphatic vessels into postsentinel lymph nodes. However, the mechanisms of consecutive lymph node colonization are unknown. Through t...