Postremission therapy in patients with acute myeloid leukemia (AML) may consist of continuing chemotherapy or transplantation using either autologous or allogeneic stem cells. Patients with favorable subtypes of AML generally receive chemotherapeutic consolidation, although recent studies have also suggested favorable outcome after hematopoietic stem cell transplantation (HSCT). Although alloge...

Articles should focus on stem cell biology and may include the following topics: Stem cell properties § § Types, including hematopoietic stem cells, embryonic stem cells, mesenchymal stem cells and induced pluripotent stem cells, plasticity and immunophenotype. Stem cell biology § § Microenvironment niches, including bone marrow and fetal liver, gene regulation including that of transcription f...

stem cells are undifferentiated biological cells that can differentiate into specialized cells and can divide (through mitosis) to produce more stem cells. they are found in multicellular organisms. in mammals, there are two broad types of stem cells: embryonic stem cells, which are isolated from the inner cell mass of blastocysts, and adult stem cells, which are found in various tissues. in ad...

Hematopoietic stem cell transplantation (HSCT) has proven successful for the treatment of a host of genetic and malignant diseases of the blood, but immune barriers to allogeneic tissue transplantation have hindered wider application. Likewise, gene therapy now appears effective in the treatment of various forms of immune deficiency, and yet insertional mutagenesis from viral gene transfer has ...

ABSTRACT Objectives: to assess/correlate health-related quality of life with the social dimension hematopoietic, autologous and allogeneic stem cell transplant patients in three years post-transplant. Methods: longitudinal, observational study 55 patients, a reference hospital Latin America, from September 2013 February 2019, using Quality Life Questionnaire-Core Functional Assessment Cancer Th...

OBJECTIVE Stem cell transplantation is usually performed in an effort to extend the patient's life span and to improve their quality of life. This study was conducted to determine the postoperative physiological effects experienced by patients who had undergone autologous and allogeneic stem cell transplantation. METHODS The research is a descriptive study conducted with a sample of 60 patien...

From ten patients with advanced malignant disease involving the bone marrow, autologous hematopoietic stem cells were collected from the peripheral blood during eight four-hour pheresis procedures and cryopreserved. No manipulations to increase the number of stem cells circulating in the blood were used during the collections. Following marrow ablative chemotherapy or chemoradiotherapy. the aut...

The objective of the research was to determine effect educational intervention based on Bandura’s Social Cognitive Learning Theory care dependency and symptom management after hematopoietic stem cell transplantation.
 Methods. This randomized controlled trial conducted between January 2019 February 2020 at Hematopoietic Stem Cell Transplantation Center. All patients were randomly divided i...