Facial feedback mechanisms of adolescents with Autistic Spectrum Disorders (ASD) were investigated utilizing three studies. Facial expressions, which became activated via automatic (Studies 1 and 2) or intentional (Study 2) mimicry, or via holding a pen between the teeth (Study 3), influenced corresponding emotions for controls, while individuals with ASD remained emotionally unaffected. Thus, ...

OBJECTIVES It has been suggested that some amino acids are involved in the pathogenesis of autistic disorders. The aim of the study was to evaluate the plasma amino acids profile in young males with autism. METHODS Total of 27 autistic boys (aged 2-10 years, the study group) without any metabolic disorders and 13 healthy boys (aged 2-9 years, control group) were included in the study. In all ...

This chapter provides a comprehensive review of twin studies in the autism fi eld. While family studies have also made a substantial contribution to our understanding of autism, these have not been reviewed here for the practical reason of space and because several informative reviews of family studies of autism are available (e.g., Bailey, Palferman, Heavey, & Le Couteur, 1998 ; Sucksmith, Rot...

Autism is a behavior disorder with genetic influences indicated from twin and family studies and from the co-occurrence of autism with known genetic disorders. Tuberous sclerosis complex (TSC) is a known genetic disorder with behavioral manifestations including autism. A literature review of these two disorders substantiates a significant association of autism and TSC with 17-58% of TSC subject...

In humans, behaviors associated with autism and antisociality, disorders characterized by distinct social impairments, can be viewed as quantitative traits that range from frank impairment to normal variation, as found in the general population. Neuroimaging investigations of autism and antisociality demonstrate diagnostically specific aberrant cortical brain structure. However, little is known...

Autistic-spectrum disorder is approximately half as common as schizophrenia but its cause remains unknown. Recent studies have begun to clarify the underlying neuroanatomical abnormalities and brain-behaviour relationships in autism. In the past decade, great advances have been made in our understanding of the neurobiological basis of autism.

background and objective: background: the present study investigates the relationship between attention deficit hyperactive disorder (adhd) and the severity of symptoms in children with autistic spectrum disorder. methods: the study was conducted on 80 patients with autistic spectrum disorder visiting child psychiatric clinic of tehran psychiatric institute. the severity of autistic symptoms wa...