A quarter of a century ago M r H arold MacMillan delivered his famous Winds o f Change speech in Cape Town. In 1975 Dr. W olff Bodenstein, in de­ livering a paper on prim ary health care, referred to the storms o f change. Now, a decade later, John Naisbitt speaks of megatrends when elaborating on change on a worldwide scale from an industrial society to an inform ational society. Alvin Toffler...

Objective. Fluoroquinolone antibiotics have been associated with tendinitis and tendon rupture. In this paper we report on the followup of 42 spontaneous reports of fluoroquinolone-associated tendon disorders. Methods. This study is based on cases of fluoroquinolone-associated tendon disorders reported to the Netherlands Pharmacovigilance Foundation Lareb and the Drug Safety Unit of the Inspect...

Disease caused by Sarcocystis spp are associated with a variety of clinical signs including abortion, hemorrhages, hair loss, muscular disease, and neurological dysfunction. In horses, clinical disease is associated with Sarcocystis fayeri and S neurona. The genesis of and clinical progression of disease caused by these protozoans in horses is not well defined but acute, chronic, and relapsing ...

Mild (140 to 159/90 to 99 mmHg) or moderate (160 to 179/100 to 109 mmHg) chronic arterial hypertension does not appear to cause headache. Whether moderate hypertension predisposes patients to headache at all remains controversial, but there is little evidence that it does. Ambulatory blood pressure monitoring in patients with mild and moderate hypertension has shown no convincing relationship b...

„Tief im Westen...“ fand an der Medizinischen Fakultät der Ruhr-Universität Bochum vom 23. bis 25. September 2010 die Jahrestagung der Gesellschaft für Medizinische Ausbildung unter dem Thema „Viel verändert – viel erreicht? Bilanz und Zukunft der Studienreformen“ statt. 7 Jahre neue ärztliche Approbationsordnung, Erfahrungen mit denModellstudiengängen und reformierten Regelstudiengängen, Innov...

BACKGROUND It has been reported that subjects of African descent present with heart failure at a younger age and because of different causes than whites. We present contemporary data from UK Afro-Caribbean patients in London. METHODS AND RESULTS All patients with heart failure presenting to St George's Hospital Heart Failure clinic between 2005 and 2012 were included (n=1392). Patients were p...

Abstract Recent advances in network science have resulted two distinct research directions aimed at augmenting and enhancing representations for complex networks. The first direction, that of high-order modeling, aims to focus on connectivity between sets nodes rather than pairs, whereas the second one, feature-rich augmentation, incorporates into a all those elements are driven by information ...