The interval coding hypothesis suggests that the processing that occurs, due to odor exposure, inside an olfactory bulb glomerulus work to create an interval code over the concentration range, so that different principal cells respond the strongest to different parts of that range. The goal of this project was to investigate the interval coding hypothesis with respect to function and biological...

A purpose of chemical health risk assessment is to characterize the nature and size of the health risk associated with exposure to chemicals, including identification of a dose below which toxic effects are not expected or negligible. This is usually based on analysis of doseresponse data from toxicity studies on animals. Traditionally the dose-response in animals has been analyzed employing th...

In the world of CAD and GIS there is a growing need for storing spatial information in neutral contexts. Storing the information in a database rather than in files gives rise to greater options concerning what can be done with the information. Being able to perform analyses on spatial information is an area of interest for many companies. In particular since analyses provide foundations for pla...

We demonstrate that viscoelastic mechanics of striated muscle, measured as elastic and viscous moduli, emerge directly from the myosin crossbridge attachment time, t(att), also called time-on. The distribution of t(att) was modeled using a gamma distribution with shape parameter, p, and scale parameter, β. At 5 mM MgATP, β was similar between mouse α-MyHC (16.0 ± 3.7 ms) and β-MyHC (17.9 ± 2.0 ...

We present an approach and an associated computer program (ATT-Meta) which can interpret novel uses of familiar metaphors. ATT-Meta performs sophisticated reasoning with uncertainty of a kind that is required for reasoning about the content of metaphorical utterances. ATT-Meta’s handling of uncertainty is qualitative and handles potential conflicts between different lines of reasoning or argume...

Introduction Several studies have demonstrated that DWI lesion conspicuity is related to the duration of transient ischaemic attack (TIA) symptoms [1, 2]. In minor ischaemic stroke or TIA (minS/TIA) the perfusion deficit will resolve over the time span of several days to one week [3, 4]. The relationship between a DWI lesion and perfusion deficit, however, remains controversial, motivating the ...

The main aim of this thesis was to study domestication effects on foraging behaviour in chickens and to investigate whether and how domestication and selection for high production have influenced adaptability in chickens. Two domestic strains of chickens (egg layers and meat type chickens) and their wild ancestor, the red jungle fowl (RJF) were compared in different test situations with respect...

The project evaluates how well a haptic device can be used to interact with a visualization of volumetric data. Since the interface to the haptic device require explicit surface descriptions, triangles had to be constructed from the volumetric data. The algorithm used to extract these triangles is marching cubes. The triangles produced by marching cubes are then transmitted to the haptic device...

A68, or PHF-tau, is an abnormally phosphorylated form of the microtubule-associated protein tau, which is a primary protein constituent of paired helical filaments (PHFs) and, ultimately, of Alzheimer's disease-associated neurofibrillary tangles (NFTs). Previously, we have shown that in heat-shocked neuronal PC12 cells, tau is hyperphosphorylated and transformed to an A68-like state as determin...

Web usage mining aims at characterizing user navigation on websites by applying techniques available through machine learning to server log data. In doing so, it is implicitly assumed that the requests made by a user to the server during one session capture the actual sequence of pages viewed by that user. In literature, this page-view sequence is referred to as “clickstream”. However, certain ...