نتایج جستجو برای: ati
تعداد نتایج: 1544 فیلتر نتایج به سال:
One of the modern methods protecting against building heat losses is active thermal insulation (ATI). In winter conditions, ATI works by supplying into envelope, which increases temperature in layer. A low-temperature renewable energy medium feeds layer directly, e.g., through solar or geothermal energy. model for transfer envelope with an was developed. The numerical simulations verified simpl...
Abstract BACKGROUND Subcutaneous administration of infliximab shows an increased benefit in terms pharmacokinetics and pharmacodynamics effects compared to the intravenous infliximab. The practical question arises whether routine refractory CD patients who have failed prior biological therapy will provide "biobetter" clinical efficacy. AIMS We propose a single center study designed evaluate SC-...
The role of trough serum infliximab (s-IFX) and antibodies toward IFX (ATI) during maintenance treatment remains unclear in children. The aim of the present study was to investigate trough s-IFX and ATI to identify any correlation with inflammatory activity and clinical response in a pediatric inflammatory bowel disease (IBD) cohort. We investigated the s-IFX trough levels in pediatric IBD pati...
Identification of an ABCB/P-glycoprotein-specific inhibitor of auxin transport by chemical genomics.
Plant development and physiology are widely determined by the polar transport of the signaling molecule auxin. This process is controlled on the cellular efflux level catalyzed by members of the PIN (pin-formed) and ABCB (ATP-binding cassette protein subfamily B)/P-glycoprotein family that can function independently and coordinately. In this study, we have identified by means of chemical genomi...
BACKGROUND Cigarette smoke (CS) is a highly complex mixture and many of its components are known carcinogens, mutagens, and other toxic substances. CS induces oxidative stress and cell death, and this cell toxicity plays a key role in the pathogenesis of several pulmonary diseases. METHODOLOGY/PRINCIPAL FINDINGS We studied the effect of cigarette smoke extract (CSE) in human alveolar epitheli...
BACKGROUND The Infliximab, has proven effective in treating rheumatoid arthritis (RA). A good clinical response is usually associated with high serum drug levels. Development of antibodies toward Infliximab (ATI) can increase drug clearance, leading to treatment failure. AIMS To analyze whether serum Infliximab trough levels (ITL) at the induction phase are associated with Infliximab clearanc...
The fluid that fills the alveolar spaces in the fetal lung is cleared shortly after birth, mainly as a consequence of active transport of sodium ions (Na ) across the alveolar epithelium. This transport establishes an osmotic gradient that favors reabsorption of intra-alveolar fluid.1 Studies that demonstrate both the reabsorption of intratracheally instilled isotonic fluid or plasma from the a...
This study used micro-computed tomography (micro-CT) to evaluate the fit of the master gutta-percha cone at time of cone fit, gutta-percha volume in the filling material, and the filling material volume in relation to the canal at the apical limit of the working length. Root canals of 20 maxillary central incisors were prepared with rotary instruments and distributed into two groups (n=10). The...
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