نتایج جستجو برای: atenolol

تعداد نتایج: 2057  

1999
Martin Hausberg Michael Barenbrock Helge Hohage Susanne Müller Stefan Heidenreich Karl-Heinz Rahn

Angiotensin-converting enzyme (ACE) inhibitors have been shown to slow the progression of chronic renal failure. However, the value of ACE inhibitors for the treatment of hypertension in renal allograft recipients has not been established. ACE inhibitors dilate the efferent glomerular arteriole, an effect that may aggravate the decrease in glomerular filtration rate resulting from cyclosporine-...

A Kulkarni M Bhatia

This study was performed to design bilayer regioselective floating tablets of atenolol and lovastatin to give immediate release of lovastatin and sustained release of atenolol. Bilayer floating tablets comprised two layers, i.e immediate release and controlled release layers. The immediate release layer comprised sodium starch glycollate as a super disintegrant and the sustained release layer c...

2007
Rafael N. PEREIRA Bruno R. VALENTE Ariane P. CRUZ Talize FOPPA Fabio S. MURAKAMI Marcos A. S. SILVA

A thermoanalyical study of pure atenolol and a commercial tablets containinf the drug were carried out using thermogravimetric (TG) and differencial scanning calorimetry (DSC) techniques. Nonisothermal method was employed to determine kinetics data of decomposition process. In order to evaluate interaction observed in the commercial tablets, compatibility studies of drug and excipients (microcr...

Journal: :Circulation 1981
M M Ibrahim R Mossallam

Atenolol, a cardioselective beta-adrenergic blocking agent, was given as the sole hypotensive drug for 8-12 weeks to 20 patients with hypertension of varying degrees of severity. Initial systolic blood pressure ranged from 162-238 mm Hg (mean +/- SEM 196 +/- 5.5 mm Hg) and diastolic blood pressure ranged from 105-143 mm Hg (118 +/- 2.5 mm Hg). Three patients had accelerated hypertension, six ha...

Journal: :Hypertension 1999
M Hausberg M Barenbrock H Hohage S Müller S Heidenreich K H Rahn

Angiotensin-converting enzyme (ACE) inhibitors have been shown to slow the progression of chronic renal failure. However, the value of ACE inhibitors for the treatment of hypertension in renal allograft recipients has not been established. ACE inhibitors dilate the efferent glomerular arteriole, an effect that may aggravate the decrease in glomerular filtration rate resulting from cyclosporine-...

Journal: :Hypertension 2008
Carmine Savoia Rhian M Touyz Farhad Amiri Ernesto L Schiffrin

Some antihypertensive agents may improve resistance artery remodeling in hypertensive patients whereas other agents may not, for similar blood pressure reduction. We questioned whether the selective mineralocorticoid receptor blocker eplerenone improves resistance artery remodeling in hypertensive patients versus the beta-blocker atenolol. Sixteen hypertensive patients were randomly assigned to...

Journal: :PloS one 2016
Kuan Hua Khor Tyson A Moore Ian A Shiels Ristan M Greer Thiruma V Arumugam Paul C Mills

PURPOSE Inflammation may contribute to the pathogenesis of specific cardiovascular diseases, but it is uncertain if mediators released during the inflammatory process will affect the continued efficacy of drugs used to treat clinical signs of the cardiac disease. We investigated the role of the complement 5a receptor 1 (C5aR1/CD88) in the cardiac response to inflammation or atenolol, and the ef...

Journal: :Journal of the American College of Cardiology 2010
Robyn J Tapp Andrew Sharp Alice V Stanton Eoin O'Brien Nishi Chaturvedi Neil R Poulter Peter S Sever Simon A McG Thom Alun D Hughes Jamil Mayet

OBJECTIVES We hypothesized that an amlodipine-based regimen would have more favorable effects on left ventricular (LV) diastolic function. BACKGROUND Different antihypertensive therapies may vary in their effect on LV diastolic function. METHODS The HACVD (Hypertension Associated Cardiovascular Disease) substudy of ASCOT (Anglo-Scandinavian Cardiac Outcomes Trial) collected detailed cardiov...

Journal: :Circulation 2000
E L Schiffrin J B Park H D Intengan R M Touyz

BACKGROUND Structural and functional alterations of the vasculature may contribute to complications of hypertension. Because angiotensin II may be pivotal in some of these vascular abnormalities, we tested the hypothesis that the angiotensin type 1 (AT(1)) receptor antagonist losartan, in contrast to the beta-blocker atenolol, would correct resistance artery abnormalities in patients with essen...

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