BACKGROUND Lung volume reduction (LVR) techniques improve lung function in selected patients with emphysema, but the impact of LVR procedures on the asynchronous movement of different chest wall compartments, which is a feature of emphysema, is not known. METHODS We used optoelectronic plethysmography to assess the effect of surgical and bronchoscopic LVR on chest wall asynchrony. Twenty-six ...

Monitoring of patient-ventilator interactions at the bedside involves evaluation of patient breathing pattern on ventilator settings. One goal of mechanical ventilation is to have ventilator-assisted breathing coincide with patient breathing. The objectives of this goal are to have patient breath initiation result in ventilator triggering without undue patient effort, to match assisted-breath d...

We investigated the role of attention in pairing superimposed visual features. When moving dots alternate in color and in motion direction, reports of the perceived color and motion reveal an asynchrony: the most accurate reports occur when the motion change precedes the associated color change by approximately 100ms [Moutoussis, K., & Zeki, S. (1997). A direct demonstration of perceptual async...

During metazoan development cells destined for different fates become asymmetric, not just in morphology and developmental potential but also in cell-cycle timing. A recent study has now shown that differential cell-cycle timing in the first cell divisions of the Caenorhabditis elegans embryo is in part controlled by a DNA replication checkpoint.

asynchrony were highly restrictive and may have led to selection of patients with a very unfavorable prognosis. Fourth, we agree with Dr. Gasparini and colleagues that the screening of patients suitable for CRT based on merely clinical criteria may be sufficient in specific settings. However, we are of the opinion that this simplification could increase the number of non-responders to CRT: this...

During this COVID-19 pandemic time, an unprecedented number of patients with severe respiratory illness require intensive care units (ICUs) under mechanical ventilation (MV) for sustaining life. Patient–ventilator asynchrony (PVA) is very common, and it occurs due to the mismatch between normal variability patients’ breathing patterns ventilator parameters. Asynchronies during invasive are caus...

This paper presents an initial bimodal acoustic-visual synthesis system able to generate concurrently the speech signal and a 3D animation of the speaker’s face. This is done by concatenating bimodal diphone units that consist of both acoustic and visual information. The latter is acquired using a stereovision technique. The proposed method addresses the problems of asynchrony and incoherence i...

Chronic obstructive pulmonary disease (COPD) patients often show asynchronous movement of the lower rib cage during spontaneous quiet breathing and exercise. We speculated that varying body position from seated to supine would influence rib cage asynchrony by changing the configuration of the respiratory muscles. Twenty-three severe COPD patients (forced expiratory volume in 1 s = 32.5 ± 7.0% p...

Current patient selection criteria for Cardiac Resynchronization Therapy (CRT), an efficacious treatment for heart failure, include no measure of disconjugate cardiac contractility other than prolonged QRS on electrocardiogram. Using cardiac magnetic resonance imaging, we examined the roles of cardiac asymmetry, asynchrony, and circumferential strain in DCC with the principal aim of generating ...

The contrast asynchrony is a stimulus configuration that illustrates the visual system's separable responses to luminance and luminance contrast information (Shapiro, 2008; Shapiro et al., 2004). When two disks, whose luminances modulate in phase with each other, are each surrounded by a disk, one light and one dark, observers can see both the in-phase brightness signals and the antiphase contr...