BACKGROUND: Airway remodeling in children with bronchial asthma is due to the effect of inflammatory mediators and growth factors on epithelium. Vitamin D (VitD) has immunomodulatory many diseases as asthma. The ant-inflammatory anti-fibrotic role VitD could prevent or improve air way asthmatic patients. AIM: study investigated supplementation expression transforming factor-beta (TGF-β), tumor ...

We read with interest the article by CHUNG et al. [1] about the risk of pulmonary thromboembolism in asthmatic patients. This nationwide population cohort study suggests that the risk of developing pulmonary thromboembolism significantly is increased in asthmatic patients compared to those of the general population, with a multivariable-adjusted hazard ratio of 3.24 (95% CI 1.74–6.01). The auth...

the aim of the present study was to examine the effects of a course of aerobic exercise on pulmonary function and tolerance of activity in asthmatic patients. among the asthmatic patients, 36 patients (m= 16, f= 20) were chosen after clinical examinations, pulmonary function test, skin prick test (spt) for aeroallergen and a six minute walk test (6mwt) on their own free will. a patient was said...

Results HDM-allergic individuals suffering from asthma showed striking differences regarding their IgE reactivity profiles compared to the non-asthmatic group. First, the frequency of IgE reactivity to the tested HDM allergens was up to 3fold higher in the asthmatic than in the non-asthmatic group. Seventy percent of the asthmatics reacted with 3 to 6 of the tested allergens compared to only 45...

BACKGROUND Childhood-to-adult persistent asthma is usually considered to be an atopic disease. However gastroesophageal reflux may also play an important role in this phenotype of asthma, especially when it is refractory to pulmonary medicine. METHODS Fifty-seven consecutive GERD patients who had decades of childhood-to-adult persistent asthmatic symptoms refractory to pulmonary medication we...

The clinical aspects of SARS-CoV-2 infection, as well the COVID-19 vaccines’ safety, efficacy and effectiveness in pediatric patients with asthma, are crucial to adapting management this fragile population for prevention strategies. aim narrative review was evaluate impact infection children asthma vaccination. Systematic research using principal medical databases conducted specific search quer...

an increasing number of asthmatic patients are attracted by complementary and and alternative medicine (cam). the aim of this study was to estimate the prevalence and describe the characteristics of cam use by children with asthma in a paediatric allergy clinic in istanbul, turkey.the parents of asthmatic children were invited to participate in a cross-sectional survey study. current asthma tre...

Subclinical lung function alterations can sometimes be discovered in asthmatic patients under clinical control. This study aimed to identify the burden of asthmatic children with subclinical airways abnormalities who may benefit from an adjustment in asthma therapy. 134 6-to-17-year-old asthmatic children were enrolled. Of them, 98 presented apparently under clinical control disease and all per...