نتایج جستجو برای: associated lipocalin

تعداد نتایج: 1521908  

2012
Fernanda Marques Sandro D. Mesquita João C. Sousa Giovanni Coppola Fuying Gao Daniel H. Geschwind Sandra Columba-Cabezas Francesca Aloisi Matilda Degn João J. Cerqueira Nuno Sousa Margarida Correia-Neves Joana A. Palha

Multiple sclerosis (MS) is a demyelinating disease that causes major neurological disability in young adults. A definitive diagnosis at the time of the first episode is still lacking, but since early treatment leads to better prognosis, the search for early biomarkers is needed. Here we characterized the transcriptome of the choroid plexus (CP), which is part of the blood-brain barriers (BBBs) ...

Journal: :Molecular biology and evolution 2000
M D Ganfornina G Gutiérrez M Bastiani D Sánchez

The lipocalins are a family of extracellular proteins that bind and transport small hydrophobic molecules. They are found in eubacteria and a great variety of eukaryotic cells, in which they play diverse physiological roles. We report here the detection of two new eukaryotic lipocalins and a phylogenetic analysis of 113 lipocalin family members performed with maximum-likelihood and parsimony me...

Journal: :Scandinavian Journal of Clinical and Laboratory Investigation 2008

Journal: :Biochemical and biophysical research communications 1999
O K Gasymov A R Abduragimov T N Yusifov B J Glasgow

The interaction of human tear lipocalin with lysozyme and lactoferrin was studied by electron paramagnetic resonance (EPR) spectroscopy. TL mutants I98C and F99C were spin labeled with MTSL and its derivative. The spectra demonstrated that at sites C98 and C99 the mobility of the nitroxides was reduced in the presence of lysozyme, lactoferrin, but not albumin. The reduced mobility was manifeste...

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