This letter is in response to the article by Dr Anirudh Malpani regarding family balancing by preimplantation genetic diagnosis (PGD) (Malpani et al., 2002). We wish to place on record that the technique of sex selection by PGD is proscribed by the Indian Council of Medical Research (ICMR, 2000). Draft guidelines for the practice of assisted reproduction, which have been formulated and which wi...

fertilization is triggered by changes in intracellular calcium concentration. in mammals, these transients in ooplasmic calcium concentration take the form of repetitive spikes, so called calcium oscillations (ca2+-oscillations). these oscillations are important for relieve of meiotic arrest and to induce all the other events of oocyte activation. although a surface mediated way of oocyte activ...