The aim of current study was to investigate the changes in the quality parameters of Holstein bull semen during the heat stress and the effect of feeding a source of omega-3 fatty acids in this period. Samples were obtained from 19 Holstein bulls during the expected time of heat stress in Iran (June to September 2009). Control group (n=10) were fed a standard concentrate feed while treatment gr...

Original works by W. D. Miller 1 in the late 1800s and early 1900s, seem to be the earliest review in English of the erosion-abrasion issue as it relates to tooth brushing and dentifrices. Miller discussed wasting away of the tooth at the neck as "very often taking a form as though produced by a three-cornered file (p. 2).” 1 Possible causes of wasting away mentioned in the literature at that t...

Grape peel and seed are good sources of important bioactive components such as phenolics, anthocyanins and antioxidants. Recovery of these components and their proper utilization is important for the development of functional foods. We have utilized the extracts of grape peel and seed obtained by ultrasonic-assisted (UAE) and supercritical fluid extractions (SFE) for the enrichment of Campbell ...

Porous and robust 12-connected metal-organic frameworks (MOFs) were constructed by linking tetranuclear lanthanide (Ln) carbonate clusters with organoboron-derived tricarboxylate bridging ligands. The high-connectivity Ln-MOFs feature remarkable thermal and hydrolytic stability and a large number of isolated Lewis acid B(III) and Ln(III) sites on the pore surfaces. The Nd-MOF assisted with sodi...

Nucleic acid molecules are important therapeutic agents in the field of antisense oligonucleotide, RNA interference, and gene therapies. Since nucleic acids are not able to cross cell membranes and enter efficiently into cells on their own, the development of efficient, safe, and precise delivery systems is the crucial challenge for development of nucleic acid therapeutics. For the delivery of ...

Genotoxic carcinogens interact with nucleic acids and proteins to yield covalently bound products (adducts), the quantitative determination of which has been proposed as a biomonitor of human exposure to carcinogens. Mass spectrometry is playing a leading role both in the structural characterisation and in the quantitative determination of these carcinogen adducts. In particular electrospray io...

Based on structural analysis of the human 2-oxoglutarate (2OG) dependent JMJD2 histone N(ε)-methyl lysyl demethylase family, 3-substituted pyridine 2,4-dicarboxylic acids were identified as potential inhibitors with possible selectivity over other human 2OG oxygenases. Microwave-assisted palladium-catalysed cross coupling methodology was developed to install a diverse set of substituents on the...

Mass spectrometry has become an increasingly important tool of high accuracy, efficiency, and speed for the routine analysis of nucleic acids. To make it useful for large-scale sequencing of genomic material as required for example in genotyping and clinical diagnosis, it is necessary to find approaches that allow the analysis of sequences much larger than the 100 nucleotides currently possible...

This paper describes a comparative study of extraction methods of terpenes (terpenic alcohols and phytosterols), fatty acids and Vitamin E from leaves of Piper gaudichaudianum Kunth. The analysis of extracts was done by gas chromatography with mass spectrometric detection. The identification and quantification was made by co-injections of the extract with certified standards. The use of pressur...