Abstract Background Severe secondary mitral regurgitation (MR) worsens prognosis in patients with medically managed heart failure (HF). In treated by left ventricular assist device (LVAD), it is unclear whether severe MR should be corrected at time of LVAD implantation. Purpose To evaluate impact therapy on and non-severe over 1 year. Methods Retrospective single centre study consecutive who un...

Eighteen percent of heart specimens with isolated ventricular septal defect also had a floppy mitral valve. There was no statistical difference in the incidence of floppy mitral valve in the three age groups considered (less than 1 year, 1 to 16 years and 17 to 91 years). In no patient was a floppy mitral valve considered to be the cause of death. Complications of floppy mitral valve (ruptured ...

OBJECTIVES To investigate the effects of transvalvar flow rate on aortic valve resistance and valve area after percutaneous transvenous balloon dilatation of the mitral valve in a homogeneous group of patients with rheumatic heart disease. DESIGN Retrospective analysis of 12 patients with combined aortic and mitral stenosis who had undergone balloon dilatation of the mitral valve over a perio...

Transcatheter mitral interventions have been developed to address an unmet need, and as alternatives to surgery in patients at high risk or considered inoperable. Beyond MitraClip therapy, alternative repair technologies are being developed to expand the armamentarium of transcatheter intervention. Recently, the feasibility of transcatheter mitral valve implantation in native non-calcified valv...

Concomitant aortic and mitral valve replacement or concomitant aortic valve replacement and mitral repair can be a challenge for the cardiac surgeon: in particular, because of their structure and design, two bioprosthetic heart valves or an aortic valve prosthesis and a rigid mitral ring can interfere at the level of the mitroaortic junction. Therefore, when a mitral bioprosthesis or a rigid mi...

Sir, I read with interest the article on Prinzmetal's angina and coronary artery spasm by Huckell and coworkers (Br Heart J 1981; 45: 649-55). The authors mentioned the association of mitral valve prolapse in eight of their 18 patients with Prinzmetal's angina, and wondered whether this finding was causative or coincidental, or whether patients with mitral prolapse were more prone to develop co...

OBJECTIVES Although mitral valve repair is rarely required in neonates, this population is considered to be at high risk for adverse outcomes. The aim of this study was to review the indications for surgery, mechanisms, repair techniques, and mid-term outcomes of neonatal mitral valve repair. METHODS The demographic, procedural, and outcome data were obtained for all neonates who underwent mi...

The therapeutic implications of bicuspid aortic valve associations have come under scrutiny in the transcatheter aortic valve implantation era. We evaluate the spectrum of mitral valve disease in patients with bicuspid aortic valves to determine the need for closer echocardiographic scrutiny/follow-up of the mitral valve. A retrospective analysis of echocardiograms done at a referral hospital o...

A new echocardiographic index of mitral valve diastolic closure, based on the rate of diastolic apposition of the anterior and posterior mitral leaflet echoes, was measured in 40 patients with mitral stenosis. This mitral valve closure index correlated highly significantly with the mitral valve orifice area (calculated from the Gorlin formula) (r = 0-87). Correlation between the diastolic closu...

A 47 year-old female died after mitral valve replacement. Post-cardiopulmonary bypass right ventricle was not able to pump despite good left ventricular contractility. At microscopic examination, diffuse right ventricular fatty infiltration was found. We found no previous report of this pathology in patients with mitral stenosis