To elucidate the role of (1-->3)-beta-D-glucan in pulmonary aspergilloma, serum concentrations of (1-->3)-beta-D-glucan were measured repeatedly for as long as 10 months in eight patients. In four patients with inactive disease, concentrations of (1-->3)-beta-D-glucan were in the normal range.The concentrations of (1-->3)-beta-D-glucan increased in two patients, although the disease was inactiv...

Saprophytic infestation with Aspergillus was observed in pathologic specimens of primary squamous cell lung carcinoma. In one case, the fungus grew in cystic scarred parenchyma and bronchi distal to an obstructing carcinoma of a segment bronchus. In the other, fungi colonized the inner surface of a peripheral cavitary carcinoma. Neither patient had roentgenographic evidence of aspergilloma and ...

A 52-year-old woman presented complaining of intermittent episodes of hemoptysis for over 40 years. Chest computed tomography (CT) showed a cavitary lesion (5.5 × 5.3 cm) in the left upper lobe with heterogeneous components. The radiologic manifestations hinted a fungus ball (Fig 1a). Bronchoscopic biopsy and bronchoalveolar lavage failed to identify tumor cells or pathogens. A serum tuberculos...

A 30-year-old male and a 40-year-old female presented with Aspergillus fungal granuloma in the cere bral locations involving the gasserian ganglion and its divisions in one case and was densely adherent to the lateral dural wall of the cavernous sinus in the other. Both patients were otherwise healthy with no evidence of immuno-suppression. The lesions resembled benign tumor on preoperative ima...