BACKGROUND AND AIMS Acute hepatic injury causes systematic inflammatory responses which may finally lead to functional disturbances in remote organs. In this study, the effects of an inhibitor of inflammatory cytokines (pentoxifylline, PTX) and a well-known antioxidant, N-acetylcysteine (NAC), were evaluated on renal damage and oxidative stress following liver ischemia reperfusion (IR). METHO...

As well-being foods pursuing healthy life are becoming popular, interest in Rubus coreanus Miquel (RCM) fruit, a type of Korean blackberry, is increasing due to its medicinal actions including protecting the liver, brightening the eyes, and alleviating diabetes. This study was carried out to evaluate the hepatoprotective effects of RCM concentrates on liver injuries induced by carbon tetrachlor...

Background:Musa acuminata fruit peels are used in the northern part of Nigeria for the treatment of hypertension and other cardiovascular related diseases. The effects of aqueous extracts of ripped fruit peel of three cultivars of Musa acuminata (Saro, Ominni and Oranta) on the hepatic and renal parameters of normal rats were examined. Methods: Fruit peel aqueous extracts (FPAE) of the 3 cultiv...

Objectives: To contribute to case management algorithms and guidelines by evaluating the clinical symptoms, laboratory data, risk factors mortality rates of patients admitted health institutions with tick bite in Tokat. 
 Methods: The virus determination was made from blood conventional PCR 141 patient. Epidemiological data such as socio-demographic variables were compared biochemical hema...

This study investigated the inhibitory effect of aqueous extract of Trigonella foenum-graecum seeds (AqE-TFG) on fat accumulation and dyslipidemia in high fat diet- (HFD-) induced obese rats. Female Wistar rats were fed with HFD ad libitum, and the rats on HFD were treated orally with AqE-TFG or orlistat ((HFD for 28 days+AqE-TFG (0.5 and 1.0 g/kg) or orlistat (10 mg/kg) from day 8 to 28), resp...

Two new flavonoids, takakin 7-O-glucoside (1) and (2) bucegin 7-O-glucoside, and six other known compounds (3-8), takakin, isosctullarien, its 7-O-glucoside, takakin 8-O-glucoside, xanthotoxin and esculetin, were separated and identified from Glossostemon bruguieri. The new compounds were characterized using modern spectroscopic techniques, including UV spectroscopy, proton nuclear resonance (1...

Several homeopathic remedies, namely, Pulsatilla Nigricans (30th potency), Ceanothus Americanus (both mother tincture and 6th potency) and Ferrum Metallicum (30th potency) selected as per similia principles were administered to 38 thalassemic patients receiving Hydroxyurea (HU) therapy for a varying period of time. Levels of serum ferritin (SF), fetal hemoglobin (HbF), hemoglobin (Hb), platelet...

Oxidative stress and genotoxicity induced by intraperitoneally implanted polycaprolactone (PCL) were evaluated in present study. In an effort to assess oxidative stress induced liver injury, we measured hematological indices, biochemical parameters of liver function and levels of oxidative stress biomarkers such as lipid peroxidation (LPO), 8hydroxy-2’deoxy guanosine (8-OHdG), reduced glutathio...

The present study focuses on the role of Costus pictus extract (CPE) against the oxidative stress caused by hypeglycemia in liver and kidney of alloxon administered rats.Hyperglycemic rats were administered with two dose levels(200 and 400mg/kg body weight) of CPE for 30 days.At the end of treatment,blood glucose,serum marker enzymes alanine amino transfrease(ALT),aspartate amino transferase(AS...

The antiplasmodial, analgesic, antiinflammatory and chronic dose effects of methanolic extract of Chrozophora senegalenesis A. Juss were studied in mice. Plasmodium berghei (NK 65 chloroquine sensitive strain) was inoculated into eighteen mice assigned to 3 groups of 6 mice each . Group I was treated with 75mg/kg bw C. Senegalensis, group II with 5mg/kg bw chloroquine phosphate (standard) and g...