نتایج جستجو برای: asian continental ancestry group
تعداد نتایج: 1066264 فیلتر نتایج به سال:
BACKGROUND Genome-wide association studies have identified several genetic loci associated with variation in resting heart rate in European and Asian populations. No study has evaluated genetic variants associated with heart rate in African Americans. OBJECTIVE To identify novel genetic variants associated with resting heart rate in African Americans. METHODS Ten cohort studies participatin...
Many aspects of the historical relationships between populations in a species are reflected in genetic data. Inferring these relationships from genetic data, however, remains a challenging task. In this paper, we present a statistical model for inferring the patterns of population splits and mixtures in multiple populations. In our model, the sampled populations in a species are related to thei...
Abstract Background The prevalence of open-angle glaucoma (OAG) varies from 0.5% to 7.0% among populations diverse ancestry, suggesting the existence genetic differences. purposes this study were provide insights into causes OAG, which can result in and phenotype differences ancestry for compare allele frequencies intraocular pressure (IOP) elevation-related SNPs OAG Koreans other ethnic groups...
Pan-Asian monsoon water isotope variability is found accompanied by a continental-scale hydroclimate footprint.
Hair morphology is highly differentiated between populations and among people of European ancestry. Whereas hair morphology in East Asian populations has been studied extensively, relatively little is known about the genetics of this trait in Europeans. We performed a genome-wide association scan for hair morphology (straight, wavy, curly) in three Australian samples of European descent. All th...
The domestication and development of cattle has considerably impacted human societies, but the histories of cattle breeds and populations have been poorly understood especially for African, Asian, and American breeds. Using genotypes from 43,043 autosomal single nucleotide polymorphism markers scored in 1,543 animals, we evaluate the population structure of 134 domesticated bovid breeds. Regard...
In a consortium including 23 637 breast cancer patients and 25 579 controls of East Asian ancestry, we investigated 70 single-nucleotide polymorphisms (SNPs) in 67 independent breast cancer susceptibility loci recently identified by genome-wide association studies (GWASs) conducted primarily in European-ancestry populations. SNPs in 31 loci showed an association with breast cancer risk at P < 0...
The ancestry of the Colombian population comprises a large number of well differentiated Native communities belonging to diverse linguistic groups. In the late fifteenth century, a process of admixture was initiated with the arrival of the Europeans, and several years later, Africans also became part of the Colombian population. Therefore, the genepool of the current Colombian population result...
BACKGROUND Age at natural menopause (ANM) is a complex trait with high heritability and is associated with several major hormonal-related diseases. Recently, several genome-wide association studies (GWAS), conducted exclusively among women of European ancestry, have discovered dozens of genetic loci influencing ANM. No study has been conducted to evaluate whether these findings can be generaliz...
The enormous genetic diversity in South Asia resulting from a long and complex admixture history resulted the emergence of variation various traits variations disease susceptibility. Neuropsychological disorders are one such example that shows at population level. In this study, we aimed understanding neuropsychological level among Asian populations by curating, comparing contrasting single nuc...
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