The specific binding of the NMDA receptor (NR) channel ligand [(3)H]MK-801 to rat brain membranes is sensitive to positively charged buffer ingredients as to tris(hydroxymethyl)aminomethane (Tris), to Na(+), or to protons. Here we demonstrate that 16 non-competitive NR antagonists, including 5 long-chain diamines, classical NR channel blockers and several less known compounds, differ widely in ...

The "small” spout, 19/64” or 5/16” in diameter, has been widely available to maple producers since the mid to late 1990's as a "healthy" alternative to the traditional 7/16” spout. While now in general use by producers in some regions, particularly those collecting sap by vacuum, the utility of these smaller spouts is still questioned by many sugarmakers, particularly those collecting sap by gr...

The origin of human chromosomes (HSA) 7, 16, and 19 was studied by comparing data obtained from chromosome banding, chromosome painting, and gene mapping in species belonging to 11 orders of placental mammals (Eutherians). This allowed us to propose the reconstruction of their presumed ancestral forms. The HSA7 homologs were composed of two parts, the largest forming an acrocentric. The smalles...

0191-8869/$ see front matter 2011 Elsevier Ltd. A doi:10.1016/j.paid.2011.02.028 ⇑ Corresponding author. E-mail address: [email protected] (R. Lynn). This paper presents the results of a longitudinal study of sex differences in intelligence as a test of Lynn’s (1994) hypothesis that from the age of 16 years males develop higher average intelligence than females. The results show that at the ages...

Target Audience: RF Engineers, UHF Labs, Researchers interested in pTX, TOF and ASL Purpose The aim of this work was to develop a 7 Tesla Arterial Spin Labeling (ASL) [1,2] transceiver coil array capable of being used as a stand-alone array [3,4] or in combination with an additional transceiver head array [5]. The transceiver design is potentially beneficial at 7T since it allows for Radio Freq...

Strategies that enhance the efficacy of adoptive therapy involve intrinsic factors such as the selection of desired effector cells and extrinsic factors such as patient conditioning. Ex vivo expanded antigen-specific T cell clones allows us to evaluate these factors in clinical trials for the treatment of patients with metastatic melanoma. In one trial, adoptively transferred antigen-specific C...

Glutamate receptors may play a critical role in the refinement of developing synapses. The lateral superior olivary nucleus (LSO)-medial nucleus of trapezoid body (MNTB) synaptic transmission in the mammalian auditory brain stem mediate many excitatory transmitters such as glutamate, which is a useful model to study excitatory synaptic development. Hearing deficits are often accompanied by chan...

— — — 3:26A 3:29A 3:31A 3:35A 3:37A 3:39A 3:41A 3:42A 3:44A 3:48A 3:51A 3:53A 3:55A 3:58A 4:04A 4:06A — — — 3:47 3:50 3:52 3:56 3:58 4:00 4:02 4:03 4:05 4:09 4:12 4:14 4:16 4:19 4:25 4:27 — — — 3:59 4:02 4:04 4:08 4:10 4:12 4:14 4:15 4:17 4:21 4:24 4:26 4:28 4:31 4:37 4:39 — — — 4:11 4:14 4:16 4:20 4:22 4:24 4:26 4:27 4:29 4:33 4:36 4:38 4:40 4:43 4:49 4:51 — — — 4:26 4:29 4:31 4:35 4:37 4:39 4...

This study characterized the longitudinal evolution of HPA axis functioning from 7 to 16 months of age and identified individual and environmental factors that shape changes in HPA axis functioning over time. Participants were 167 mother-infant dyads drawn from a larger longitudinal study, recruited based on maternal history of being maltreated during childhood. Salivary cortisol levels were as...

This is a status report on a companion subject to extremal combinatorics, obtained by replacing extremality properties with emergent structure, ‘phases’. We discuss phases, and phase transitions, in large graphs and large permutations, motivating and using the asymptotic formalisms of graphons for graphs and permutons for permutations. Phase structure is shown to emerge using entropy and large ...