Based on knowledge from traditional Arabic and Islamic herbal medicine, this study aims to examine the effects of extracts from Ferula assa-foetida L on male fertility and sexual functioning in rats and in man. Therefore, ethanol extract from seeds and 50% water-ethanol extracts from roots were prepared into so-called “Masculine” tablets and assessed for their safety and efficacy in enhancing m...

The current investigation was undertaken to determine the anti-inflammatory and antioxidant effects of Paederia foetida Linn. (PF) along with its mechanism of action when implemented in tissue protection. HPTLC was used in the identification of the compound quercetin, while in vitro analysis confirmed the significance of the antioxidant and anti-inflammatory action of PF. We initially demonstra...

The medicinal plants of Huang-qi (Radix Astragali) and Sheng-ma (Cimicifuga foetida) demonstrate significantly better antioxidant effects when used in combination than when used alone. However, the bioactive components and interactional mechanism underlying this synergistic action are still not well understood. In the present study, 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay ...

BACKGROUND Quorum sensing is a microbial cell-to-cell communication process. Quorum sensing bacteria produce and release extracellular messenger molecules called autoinducers. Gram-positive and Gram-negative, homoserine lactones, and oligopeptides are autoinducers used to communicate and regulate gene expression. OBJECTIVES The goal of this study was to assess the impact of subinhibitory conc...

AIM The present study was performed to investigate acute and subchronic oral toxicity of Ferula assa-foetida gum (28 days) in Sprague Dawley rats. MATERIALS AND METHODS Acute oral administration of F. assa-foetida was done as a single bolus dose up to 5 g/kg in mice and subchronic toxicity study for 28 days was done by oral administration at doses of 0 (control) and 250 mg/kg in Sprague Dawle...

BACKGROUND Cycloartane triterpenoids exhibited anticancer effects. This study aims to identify any potential novel anticancer cycloartane triterpenoids from Cimicifuga foetida L. rhizome (Sheng ma) and the mode of actions. METHODS Cycloartane triterpenoids were isolated from the C. foetida rhizome by a series of column chromatography and identified by IR, MS and NMR. Their anticancer effects ...

Introduction The earthworm coelomic fluid (ECF) has shown proven antiproliferative effect against breast, liver, gastrointestinal, and brain cancer, but it is least explored in oral cancer. The present in vitro study is an attempt to investigate the antiproliferative activity of ECF on oral cancer cell line squamous cell carcinoma (SCC)-9. Materials and Methods ECF was collected from the spec...

CURRENT SCIENCE, VOL. 90, NO. 1, 10 JANUARY 2006 100 *For correspondence. (e-mail: [email protected]) 15. Hombe Gowda, H. C., Vasudeva, R., Georgi P. Mathachen., Uma Shaanker, R. and Ganeshaiah, K. N., Breeding types in Nothapodytes nimmoniana Graham. Curr. Sci., 2002, 83, 1077–1078. 16. Ravi Kumar and Ved, D. K., 100 Red Listed Medicinal Plants of Conservation Concern in Southern Ind...

BACKGROUND The primary objective of the present investigation is to evaluate the antidiabetic, antihyperlidemic and antioxidant activity of the methanolic extract of the Paederia foetida Linn. (PF) leaf extract in the streptozotocin induced diabetic rats. METHODS Single intraperitoneal injection (IP) of streptozotocin (60 mg/kg body weight) was used for induction of diabetes is swiss albino (...