The ketogenic diet (KD), a restrictive diet, is mainly characterized by high-fat content, low or no carbohydrate and normal protein content. This review aimed to address the main syndromes diseases in which therapeutic use of KD can be beneficial. One clinical indications has been, for some time, treatment epilepsy refractory medications, with satisfactory results control seizures. Recently, st...

The Ketogenic Diet (KD) has been used in treatment of epilepsy in mainland China since 2004. Clinical indications of KD include: Glucose Transporter Type 1 (GLUT-1) deficiency, Pyruvate Dehydrogenase Deficiency (PDHD, myoclonus-astatic epilepsy (Doose syndrome), tuberous sclerosis complicated with or without epilepsy, Rett syndrome, Dravet syndrome, infantile spasms, and Landau-Kleffner syndrom...

Despite appropriate antiepileptic drug treatment, approximately one-third of humans and dogs with epilepsy continue experiencing seizures, emphasising the importance for new treatment strategies to improve the quality of life of people or dogs with epilepsy. A 6-month prospective, randomised, double-blinded, placebo-controlled cross-over dietary trial was designed to compare a ketogenic medium-...

clusters of absence seizures. The patient was born after an uncomplicated pregnancy by spontaneous delivery and an uneventful perinatal period. Growth and development were normal and she was in second grade in a regular school. Her medical history included right nephrec-tomy because of a dysplastic kidney. Since she was 5 years old her parents noted multiple daily episodes of staring, sometimes...

The ketogenic diet (KD) is an effective treatment for children with drug-resistant epilepsy and has been widely used in young children. Adult patients with intractable epilepsy would also benefit from this dietary treatment. However, only a few studies have been published, and the use of the KD in intractable epilepsy in adults has been limited. This meta-analysis summarized the findings of the...

OBJECTIVE: To find the effectiveness and tolerability of ketogenic diet (KD) for Pakistani children with refractory epilepsy. METHODS: This study was conducted at Child Neurology Department, Children's Hospital & Institute Health Multan, Pakistan. Data diagnosed patients epilepsy, not responding to ≥2 antiepileptic drugs (AEDs), were well-tolerated, adequately utilized received KD treatment...

objective epilepsy is a common disorder affecting approximately 1% of the population. it is estimated that about 20- 30% of the patients become refractory to proper medical therapies. such cases are often termed intractable. intractable epilepsy (ie) is a serious condition in children, leading to significant impairment in quality of life, as well as behavioral and psychiatric problems. in this ...