نتایج جستجو برای: arg72pro

تعداد نتایج: 196  

2014
Osamu Nunobiki Hirohide Sawada Masatsugu Ueda

To investigate the association between polymorphisms (SNP) in the p53 and murine double minute 2 homolog (MDM2) promoter 309 in cervical carcinogenesis. SNP at p53 codon 72 polymorphisms and MDM2 promoter 309 (T/G) together with human papillomavirus (HPV) types were examined in a total of 187 cervical smear samples using real time PCR. 27 cases with HPV types 16 and/or 18 had significantly high...

Journal: :Asian Pacific journal of cancer prevention : APJCP 2011
Abdul Aziz Ahmad Aizat Siti Nurfatimah Mohd Shahpudin Mohd Aminudin Mustapha Zaidi Zakaria Ahmad Shanwani Mohd Sidek Muhammad Radzi Abu Hassan Ravindran Ankathil

BACKGROUND Colorectal cancer (CRC) results from the interaction between environmental exposures and genetic predisposition factors. AIMS A case control study was designed and to investigate the genotype frequencies of P53Arg72Pro polymorphism in Malaysian CRC patients and healthy controls and to determine the associated risk of this polymorphism with CRC predisposition. METHODS In this case...

Journal: :Genetics and molecular research : GMR 2015
J Z Peng L Xue D G Liu Y H Lin

Although many epidemiologic studies have investigated the p53 codon 72 polymorphism and its association with esophageal cancer (EC) in China, definite conclusions could not be drawn. To clarify the effects of p53 codon 72 polymorphism on the risk of EC, we performed a meta-analysis on the Chinese population. A total of 13 studies including 3308 patients and 5115 controls were involved in this m...

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