نتایج جستجو برای: aquaporin 4

تعداد نتایج: 1307343  

2018
Yuki Matsumoto Mario Tsuchiya Shakespear Norshalena Chikako Kaneko Jin Kubo Teiji Yamamoto Toshiyuki Takahashi Kazuo Fujihara

A 26-year-old, 17-week pregnant woman developed aquaporin-4-IgG-positive severe longitudinally extensive transverse myelitis during the course of disseminated herpes zoster and became quadriparetic. She was unresponsive to high-dose intravenous methylprednisolone but became able to walk without assistance after intravenous immunoglobulin. One and a half months later, left optic neuritis develop...

2016
Akiko Kamegawa Yoko Hiroaki Kazutoshi Tani Yoshinori Fujiyoshi

Acetazolamide (AZA) reduces the water permeability of aquaporin-4, the predominant water channel in the brain. We determined the structure of aquaporin-4 in the presence of AZA using electron crystallography. Most of the features of the 5-Å density map were consistent with those of the previously determined atomic model. The map showed a protruding density from near the extracellular pore entra...

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