LINC01204 Negatively Regulates the Effect of MiR-214 on Lung Cancer Cell Apoptosis, Migration, Invasion and Radio-sensitivity

Objective(s): To investigate the role of miR-22 in the efficacy of combined icotinib (BPI-2009H) and pemetrexed (LY-231514) on tumor growth and apoptosis in rats with non-small cell lung cancer (NSCLC).Materials and Methods: Rats were injected with HCC827 cells, which were transfected with anti-miR-22, followed by the treatment of BPI-20...

conclusions pericardial effusion was a rare finding in this case of langerhans cell histiocytosis. pericardial effusion in langerhans cell histiocytosis, which is an unusual presentation, should be considered when the patient experiences respiratory distress. introduction langerhans cell histiocytosis (lch) is a proliferative disorder of histiocytes in multiple organs. langerhans cell histiocyt...

conclusions this report presents a new method for lung isolation in specific cases and in the absence of certain equipment. case presentation a 41-year-old woman with a history of pharyngo-laryngo-oesophagectomy (plo) and tracheostomy was a candidate for thoracic duct ligation because of chylothorax. since the patient had tracheostmy stomal stenosis, two cuffed tracheal tubes (internal diameter...

Aims: The backbone of treatment in advanced non-small cell lung cancer is platinum-based doublet chemotherapy. We intended to compare the effectiveness of two commonly used regimens in real world practice. Methods: This single institute, parallel comparative post marketing study included 100 patients with chemo-naïve advanced (stage IIIB, IV) non-small cell lung cancer and Eastern Cooperative O...

Neuroblastoma (NB) is considered one of the malignant tumors of the nervous system which originates from primordial neural crest cell and is known as the most common extra-cranial solid tumor in childhood. This tumor which is often intra-abdominal, metastases in various sites including the skull, long bones, liver, bone marrow and lymph nodes, but lung metastasis at initial diagnosis is rare (0...

inhalation delivery of aerosolized antibacterials is preferred over conventional methods of delivery for targeting lung infection. the present study is concerned with the development and characterization of a novel, spray dried, aerosolized, chitosan polyelectrolyte complex (pec) based microparticles containing antibacterials for the treatment of lung infections.chitosan polyelectrolyte complex...

Immuno-oncology marked a therapeutic revolution in the treatment of cancer. Thanks to new strategy that aims awaken immune system fight cancer cells, there has been change clinical course advanced Non- Small Cell Lung Cancer (NSCLC). Our study aimed evaluate efficacy nivolumab monotherapy patients with stage IIIB/IV non-small cell lung beyond second line. The results showed progression-free sur...