نتایج جستجو برای: apj receptor
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Chemokines have received increasing attention due to their inhibitory activities on human immunodeficiency virus type-1 (HIV-1) and simian immunodeficiency virus (SIV) replication and the potential for chemokine receptors to assist in HIV-1/SIV entry into permissive cells. Besides CD4, which is the major receptor for HIV-1 and SIV, a number of chemokine receptors including but not limited to AP...
The apelin receptor APJ belongs to the family of seventransmembrane domain receptors and is coupled to inhibitory G-proteins [1,2]. Apelin is synthesized as a 77 amino acid pre-pro-peptide that can be cleaved into fragments of different sizes that activate APJ [1,2]. Apelin peptides have been shown to affect many biological functions in mammals including the neuroendocrine, cardiovascular, and ...
OVER THE PAST 30 YEARS, THERE has been considerable interest in the elucidation of factors that mediate angiogenesis. These efforts led to the identification of factors such as vascular endothelial growth factor (VEGF), acidic and basic fibroblast growth factor (FGF-1 and -2), and angiopoietins, to name a few. Subsequent detailed investigations have revealed that finely tuned and precisely coor...
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