PURPOSE This study developed light cured dental composites with added monocalcium phosphate monohydrate (MCPM), tristrontium phosphate (TSrP) and antimicrobial polylysine (PLS). The aim was to produce composites that have enhanced water sorption induced expansion, can promote apatite precipitation and release polylysine. MATERIALS AND METHODS Experimental composite formulations consisted of l...

Bone-like apatite coating of polymeric substrates by means of biomimetic process is a possible way to enhance the bone bonding ability of the materials. The created apatite layer is believed to have an ability to provide a favorable environment for osteoblasts or osteoprogenitor cells. The purpose of this study is to obtain bone-like apatite layer onto chitosan fiber mesh tissue engineering sca...

Among bioactive ceramics, the apatite/wollastonite (A/W) glass ceramic, containing apatite and wollastonite crystals in the glassy matrix, has been largely studied because of good bioactivity and used in some fields of medicine, especially in orthopedics and dentistry. However, medical applications of bioceramic are limited to non-load bearing applications because of their poor mechanical prope...

Medial calcification in the human aorta accumulates during aging and is known to be aggravated in several diseases. Atherosclerosis, another major cause of cardiovascular calcification, shares some common aggravators. However, the mechanisms of cardiovascular calcification remain poorly understood. To elucidate the relationship between medial aortic calcification and atherosclerosis, we charact...

Corresponding author: Yuehuei H. An, MD, Department of Orthopaedic Surgery, Medical University of South Carolina, 96 Jonathan Lucas St, Suite 708, Charleston, SC 29425. Tel: (843) 792-8169; Fax: (843) 792-3674; [email protected] Figure 1. Scanning electron micrographs (SEM) of PLLA and nano apatite-PLLA scaffold surfaces prepared using sugar sphere leaching method. (A) PLLA scaffold; (B) Nano apatit...

Calcium phosphate is deposited in many diseases, but formation mechanisms remain speculative. Nanobacteria are the smallest cell-walled bacteria, only recently discovered in human and cow blood and commercial cell culture serum. In this study, we identified with energy-dispersive x-ray microanalysis and chemical analysis that all growth phases of nanobacteria produce biogenic apatite on their c...

The aim of this work was to study the influence of uncoated and apatite-coated Al2O3 implants on bone regeneration after 30 days of surgery in New Zealand white rabbits. Twelve samples of Al2O3 implants were prepared and half of them (n = 6) were apatite-coated by the modified biomimetic method. Three experimental groups were tested as Group C – control, surgery procedure without ceramic implan...

The remarkable properties of bone derive from a highly organized arrangement of coaligned nanometer-scale apatite platelets within a fibrillar collagen matrix. The origin of this arrangement is poorly understood and the crystal structures of hydroxyapatite (HAP) and the nonmineralized collagen fibrils alone do not provide an explanation. Moreover, little is known about collagen-apatite interact...

Major and minor elements of successively collected 70 Middle Triassic radiolarian bedded cherts from the Mino Belt in central Japan were studied. In order to reveal pre-diagenetic, primary geochemical signatures related to marine biogeochemical cycles, composite data of chert-shale couplets in addition to raw data were examined. The results show that Mn, Cu, Sr, Ba and P were supplied significa...