Prosthetic aortic valve and conduit dehiscence with periconduit cavity and ascending aortic aneurysm is an uncommon complication of aortic root surgery. It is usually recognizable at echocardiography due to an abnormal position of the prosthetic valve and conduit in relation to the native aortic annulus in conjunction with an abnormal echolucent periconduit space that fills with color flow. Mit...

Aortic stenosis has been shown to share the same risk factors as atherosclerosis which suggested a potential benefit from statins therapy. Fourteen studies which provided the effect of statins treatment on aortic stenosis (AS) were meta-analyzed, including 5 randomized controlled trials (RCTs) and 9 observational studies. In the RCTs, statins did not have any influence on peak aortic valve velo...

BACKGROUND Intermittent stuck valve after mechanical valve replacement surgery is a very rare and severe complication. CASE SUMMARY We present 1 case of a 53-year-old woman after aortic valve replacement for severe aortic valve stenosis combined with hypertrophy septum. She was diagnosed with intermittent stuck valve only 1 day after surgery by clinical symptoms, intraoperative transoesophage...

stanford type a acute aortic dissection (aad) is a very rare complication, with potentially lethal consequences in pregnancy. in fact, pregnancy has been regularly associated with the possibility of aortic. dissection in almost half of young women. herein, we present the case of a 38-year-old woman in her 37th week of pregnancy. the patient’s medical history was indicative of g4l2ab1(4 gestaiti...

Methods 46 patients with severe AS without obstructive coronary artery disease awaiting aortic valve replacement were studied. Transthoracic echocardiography (TTE) was used to assess aortic valve area using the continuity equation, peak aortic velocity and mean valve gradient. CMR was used to assess aortic valve morphology and to enable planimetry of aortic valve area. Two SSFP cines of the aor...

Aortic valve calcification is the most common form of valvular heart disease, but the mechanisms of calcific aortic valve disease (CAVD) are unknown. NOTCH1 mutations are associated with aortic valve malformations and adult-onset calcification in families with inherited disease. The Notch signaling pathway is critical for multiple cell differentiation processes, but its role in the development ...

case presentation a 43-year-old man was referred to our institution for a severe aortic regurgitation and an ascending aorta enlargement associated with a relapsing sub-aortic membrane, which had been treated in his childhood. he underwent a redo ascending aorta replacement and an aortic valve replacement (mechanical prosthesis) along with a resection of the relapsing sub-valvular membrane. som...

OBJECTIVES This study sought to report on the feasibility and early results of transcatheter aortic valve implantation employing a second-generation device in a series of patients with pure aortic regurgitation. BACKGROUND Efficacy and safety of transcatheter aortic valve implantation in patients with calcific aortic stenosis and high surgical risk has been demonstrated. However, experience w...

Aortic valve replacement (AVR) has been the default procedure for the surgical management of aortic valve disease, with repair techniques heterogeneously and infrequently used. However, surgical aortic valve repair has evolved with improved techniques. Yet many questions remain regarding the ideal techniques and real-world applicability and effectiveness of valve repair. The AORTA Great Debate ...

Transcatheter aortic valves have been designed to treat elderly patients considered high-risk surgical candidates. Transcatheter aortic valve embolization represents a new complication previously unreported in the surgical bioprosthetic valve literature. We report the case of a 79-year-old male who successfully underwent aortic valve replacement after transcatheter aortic valve dislodgment into...