Monosomy of chromosome 14 has been reported in only a few prenatal cases. Generally, this monosomy is associated with a mosaicism of ring chromosome 14. Ring chromosome 14 is a rare cytogenetic entity with clinical characteristics that include growth retardation, facial dysmorphia, hypotonia, seizures, and retinitis pigmentosa. Given that the majority of symptoms appear postnatally, few cases h...

angiotensin-converting enzyme (ace) inhibitors including quinapril could exert a protective effect on cardiovascular system through endothelial system in normoglycemic and diabetic rats. the present experimental work was designed to study the vascular reactivity of aortic ring segments isolated from streptozotocin (stz)-diabetic rats treated for 4 weeks with nitro-l-arginine-methyl ester (l-nam...

Aortic root dilatation was sought by echocardiography and radiology in 500 consecutive patients referred to an echocardiography laboratory from cardiac or medical clinics and wards. Forty-four of these patients (8.8%) had false echocardiographic evidence of aortic root dissection, but no clinical evidence of the disease. These false findings were attributed to the changing of the transducer ang...

Objective(s) Four novel losartan analogues 5a-d were synthesized by connecting a dihydropyridine nucleus to imidazole ring. The effects of 5a and 5b on angiotensin receptors (AT') and L-type calcium channels were investigated on isolated rat aorta. Materials and Methods Aortic rings were pre-contracted with 1 pM Angiotensin II or 80 mM KCl and relaxant effects of losartan, nifedipine, 5a and...

Two children presented with symptoms suggestive of a vascular ring. Barium esophagrams in each case showed a posterior impression caused by a retroesophageal aortic arch. Angiographic studies defined a rare form of vascular ring resulting from an ascending left-sided aorta, a descending right-sided aorta and a right-sided ligamentum arteriosum. At surgery, the diagnosis was confirmed and the an...

We report a case of a 750 grams premature female who was scheduled for surgical ligation of a patent arterial duct. Intra-operative findings showed a patent arterial duct in association to a retro-esophageal aortic arch creating a complete vascular ring around the trachea, which was successfully divided. A vascular ring should be ruled-out in premature infants prior to ductal ligation at bidime...