Abstract Enteropathogenic E. coli (EPEC) causes intestinal infections leading to severe diarrhea. EPEC attaches the host cell causing lesions epithelium coupled with effacement of microvilli. In process, actin accumulates into a pedestal-like structure under bacterial microcolonies. We designed an automated fluorescence microscopy-based screening method for discovering compounds capable inhibit...

Gastrointestinal pathogens employ a variety of mechanisms to damage host tissue, acquire nutrients, and evade treatment. To supplement broad-spectrum antimicrobials, there has been increasing interest in designing molecules that target specific taxa virulence processes. Excitingly, these antivirulence therapies may be able synthesized by gut-resident microbes, thereby enabling delivery drugs di...

the major objective in endodontic therapy is to disinfect the entire root canal system. this requires that the pulpal content be eliminated as sources of infection. this goal may be accomplished by mechanical instrumentation and chemical irrigation, in conjunction with medication of the root canal between treatment sessions. microorganisms and their by-products are considered to be the major ca...

herbal medicine can be a valuable source of assistance for traditional medicine. there are a number of herbs that can be used in conjunction with modern medicine. herbs can also be taken to aid recovery from serious diseases. although one should never aim to treat diseases such as cardiovascular disease solely with herbal medicine, the value of herbs used in tandem with modern medicine cannot b...